SCHEMBL222008

SCHEMBL222008

C=C(C)C(=O)NCc1ccc(N(CCC)CCC)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESRRG P62508 3/20 0.50
L3MBTL1 Q9Y468 3/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CNR2 P34972 1/20 0.41
ALDH1A1 P00352 3/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
RORC P51449 2/20 0.40
CNR1 P21554 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
EGFR P00533 1/20 0.38
ERBB2 P04626 1/20 0.38
NAMPT P43490 2/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL222320 0.92 EGFR (0.44) ESRRGL3MBTL1CNR2ALDH1A1KMT2A
SCHEMBL222075 0.88 ALDH1A1 (0.50) ESRRGL3MBTL1NPSR1CNR2ALDH1A1
SCHEMBL26217887 0.84 ESRRG (0.45) ESRRGL3MBTL1NPSR1CNR2ALDH1A1
SCHEMBL731190 0.82 KMT2A (0.50) L3MBTL1ALDH1A1KMT2AMEN1HTT
SCHEMBL219055 0.81 ALDH1A1 (0.55) L3MBTL1ALDH1A1KMT2AMEN1TDP1
SCHEMBL1262266 0.79 TGM2 (0.56) ESRRGL3MBTL1NPSR1CNR2ALDH1A1
SCHEMBL3869761 0.76 KDM4E (0.53) CNR2ALDH1A1KMT2AMEN1CNR1
SCHEMBL5024307 0.76 SMN1; SMN2 (0.56) L3MBTL1NPSR1ALDH1A1KMT2AMEN1
SCHEMBL202718 0.74 MEN1 (0.61) ALDH1A1KMT2AMEN1GAAKDM4E
SCHEMBL19215206 0.74 CYP4F2 (0.47) ALDH1A1KMT2AMEN1CA2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10222721-B2 Urethane foam and toner-conveying roller using the same BRIDGESTONE CORPORATION (JP) 2019-03-05 US disclosed
US-9563154-B2 Toner transfer roller and image forming device using the same BRIDGESTONE CORPORATION (JP) 2017-02-07 US disclosed
US-9316958-B2 Charge-controlled polyurethane foam and toner-conveying roller using the same BRIDGESTONE CORPORATION (JP) 2016-04-19 US disclosed
US-8088876-B2 Copolymer, resin for electrophotographic functional component parts, developing roller, and electrophotographic apparatus CANON KASEI KABUSHIKI KAISHA (JP) 2012-01-03 US disclosed
US-20110188900-A1 URETHANE FOAM AND TONER-CONVEYING ROLLER USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-08-04 US disclosed
US-20110177926-A1 CHARGE-CONTROLLED POLYURETHANE FOAM AND TONER-CONVEYING ROLLER USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-07-21 US disclosed
US-20100158579-A1 TONER TRANSFER ROLLER AND IMAGE FORMING DEVICE USING THE SAME BRIDGESTONE CORPORATION (JP) 2010-06-24 US disclosed
EP-1178360-B1 ELECTROPHOTOGRAPHING DRY-TYPE TONER AND PRODUCTION METHOD THEREFOR SEIKO EPSON CORP (JP) 2006-11-15 EP disclosed
US-6806011-B2 MICROSTRUCTURE PARTICLES COMPRISING COLORED POLYMERS, RELEASE AGENTS, BINDERS AND COATINGS, HAVING OFFSET RESISTANCE, DURABILITY AND RADIATION TRANSPARENT; ELECTROGRAPHY SEIO EPSON CORPORATION (JP) 2004-10-19 US disclosed
US-20040110078-A1 Dry toner for electrophotography, and its production process SEIKO EPSON CORPORATION 2004-06-10 US disclosed
US-6686112-B2 MIXTURE OF COLORED PARTICLES, RELEASE AGENTS AND POLYMER RESIN; OFFSET RESISTANCE SEIKO EPSON CORPORATION (JP) 2004-02-03 US disclosed
US-20020160289-A1 Electrophotographing dry-type toner and production method therefor SEIKO EPSON CORPORATION (JP) 2002-10-31 US disclosed
EP-1178360-A1 ELECTROPHOTOGRAPHING DRY-TYPE TONER AND PRODUCTION METHOD THEREFOR SEIKO EPSON CORPORATION (JP) 2002-02-06 EP disclosed