SCHEMBL222075

SCHEMBL222075

C=C(C)C(=O)NCc1ccc(N(CC)CC)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
LMNA P02545 4/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
MAPK1 P28482 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
AOC3 Q16853 1/20 0.49
ESRRB O95718 1/20 0.48
ESRRG P62508 1/20 0.48
GAA P10253 2/20 0.47
TSHR P16473 1/20 0.46
CNR1 P21554 1/20 0.46
MAPT P10636 3/20 0.44
CNR2 P34972 2/20 0.44
NOX1 Q9Y5S8 2/20 0.44
POLB P06746 2/20 0.44
MCL1 Q07820 1/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL222008 0.88 ESRRG (0.50) ALDH1A1LMNAL3MBTL1MEN1KMT2A
SCHEMBL222320 0.85 EGFR (0.44) ALDH1A1LMNAL3MBTL1MEN1KMT2A
SCHEMBL731190 0.85 KMT2A (0.50) ALDH1A1L3MBTL1MEN1KMT2AMAPT
SCHEMBL219055 0.84 ALDH1A1 (0.55) ALDH1A1L3MBTL1MEN1KMT2ATDP1
SCHEMBL3869761 0.78 KDM4E (0.53) ALDH1A1MEN1KMT2ACNR1CNR2
SCHEMBL5024307 0.78 SMN1; SMN2 (0.56) ALDH1A1LMNAL3MBTL1MEN1KMT2A
SCHEMBL1263579 0.78 TGM2 (0.59) ALDH1A1LMNAL3MBTL1MEN1KMT2A
SCHEMBL19215206 0.77 CYP4F2 (0.47) ALDH1A1MEN1KMT2AMAPTPOLB
SCHEMBL6415716 0.77 EPHX2 (0.50) ALDH1A1KMT2AESRRG
SCHEMBL202718 0.77 MEN1 (0.61) ALDH1A1MEN1KMT2AGAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10222721-B2 Urethane foam and toner-conveying roller using the same BRIDGESTONE CORPORATION (JP) 2019-03-05 US disclosed
US-9563154-B2 Toner transfer roller and image forming device using the same BRIDGESTONE CORPORATION (JP) 2017-02-07 US disclosed
US-9316958-B2 Charge-controlled polyurethane foam and toner-conveying roller using the same BRIDGESTONE CORPORATION (JP) 2016-04-19 US disclosed
US-8088876-B2 Copolymer, resin for electrophotographic functional component parts, developing roller, and electrophotographic apparatus CANON KASEI KABUSHIKI KAISHA (JP) 2012-01-03 US disclosed
US-20110188900-A1 URETHANE FOAM AND TONER-CONVEYING ROLLER USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-08-04 US disclosed
US-20110177926-A1 CHARGE-CONTROLLED POLYURETHANE FOAM AND TONER-CONVEYING ROLLER USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-07-21 US disclosed
US-20100158579-A1 TONER TRANSFER ROLLER AND IMAGE FORMING DEVICE USING THE SAME BRIDGESTONE CORPORATION (JP) 2010-06-24 US disclosed
EP-1178360-B1 ELECTROPHOTOGRAPHING DRY-TYPE TONER AND PRODUCTION METHOD THEREFOR SEIKO EPSON CORP (JP) 2006-11-15 EP disclosed
US-6806011-B2 MICROSTRUCTURE PARTICLES COMPRISING COLORED POLYMERS, RELEASE AGENTS, BINDERS AND COATINGS, HAVING OFFSET RESISTANCE, DURABILITY AND RADIATION TRANSPARENT; ELECTROGRAPHY SEIO EPSON CORPORATION (JP) 2004-10-19 US disclosed
US-20040110078-A1 Dry toner for electrophotography, and its production process SEIKO EPSON CORPORATION 2004-06-10 US disclosed
US-6686112-B2 MIXTURE OF COLORED PARTICLES, RELEASE AGENTS AND POLYMER RESIN; OFFSET RESISTANCE SEIKO EPSON CORPORATION (JP) 2004-02-03 US disclosed
US-20020160289-A1 Electrophotographing dry-type toner and production method therefor SEIKO EPSON CORPORATION (JP) 2002-10-31 US disclosed
EP-1178360-A1 ELECTROPHOTOGRAPHING DRY-TYPE TONER AND PRODUCTION METHOD THEREFOR SEIKO EPSON CORPORATION (JP) 2002-02-06 EP disclosed