Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.58 |
| ▸ | SYK | P43405 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 5/20 | 0.55 |
| ▸ | CTSL | P07711 | 5/20 | 0.53 |
| ▸ | CTSS | P25774 | 5/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 3/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28366233 | 1.00 | CTRB1 (0.58) | CTRB1SYKCTSKCTSLCTSS | |
| SCHEMBL15271597 | 1.00 | CTRB1 (0.58) | CTRB1SYKCTSKCTSLCTSS | |
| Isobutane SCHEMBL29141206 | 0.97 | CTSK (0.56) | CTRB1SYKCTSKCTSLCTSS | |
| SCHEMBL19933193 | 0.93 | CTRB1 (0.62) | CTRB1SYKCTSKCTSLCTSS | |
| SCHEMBL19519899 | 0.92 | CTSL (0.60) | CTRB1SYKCTSKCTSLCTSS | |
| SCHEMBL8352939 | 0.92 | CTSL (0.60) | CTRB1SYKCTSKCTSLCTSS | |
| SCHEMBL31479939 | 0.92 | CTSL (0.60) | CTRB1SYKCTSKCTSLCTSS | |
| SCHEMBL19050939 | 0.91 | CTSL (0.56) | CTRB1SYKCTSLCTSSSIRT2 | |
| SCHEMBL27351869 | 0.90 | SYK (0.63) | CTRB1SYKCTSKCTSLCTSS | |
| SCHEMBL15664942 | 0.88 | CTRB1 (0.61) | CTRB1SYKCTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110869375-B | 2-oxo-1-imidazolidinylimidazothiadiazole derivatives | UCB生物制药有限责任公司 | 2022-08-30 | — | — | CN | disclosed |
| US-11155564-B2 | 2-oxo-1-imidazolidinyl imidazothiadiazole derivatives | UCB Biopharma SRL | 2021-10-26 | — | — | US | disclosed |
| EP-3652182-B1 | 2-OXO-1-IMIDAZOLIDINYL IMIDAZOTHIADIAZOLE DERIVATIVES | UCB Biopharma SRL (BE) | 2021-09-08 | — | — | EP | disclosed |
| US-20200140458-A1 | 2-OXO-1-IMIDAZOLIDINYL IMIDAZOTHIADIAZOLE DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2020-05-07 | — | — | US | disclosed |
| CN-110869375-A | 2-oxo-1-imidazolidinylimidazothiadiazole derivatives | UCB生物制药有限责任公司 | 2020-03-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200140458-A1 | 2-OXO-1-IMIDAZOLIDINYL IMIDAZOTHIADIAZOLE DERIVATIVES | CYP3A4, CYP3A43, CYP3A7 | CTRB1 2139/4885SYK 2310/4885CTSK 859/4885 |
| US-11155564-B2 | 2-oxo-1-imidazolidinyl imidazothiadiazole derivatives | CYP3A4, CYP3A43, CYP3A7 | CTRB1 2139/4885SYK 2310/4885CTSK 859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.