Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435661 | 0.80 | KMT2A (0.40) | TP53OPRM1OPRL1TACR1KMT2A | |
| SCHEMBL2838092 | 0.77 | OPRM1 (0.44) | TP53OPRM1OPRL1SMN1; SMN2SOAT1 | |
| SCHEMBL10084139 | 0.70 | SLC6A4 (0.54) | OPRM1OPRL1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL9139656 | 0.70 | OPRM1 (0.60) | TP53OPRM1OPRL1SMN1; SMN2KMT2A | |
| SCHEMBL9141149 | 0.70 | OPRM1 (0.60) | TP53OPRM1OPRL1SMN1; SMN2KMT2A | |
| SCHEMBL8041567 | 0.65 | TACR1 (0.46) | OPRM1TACR1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL8333396 | 0.65 | TACR1 (0.54) | TACR1OPRD1OPRK1 | |
| SCHEMBL18445949 | 0.65 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2ALMNAPOLBMAPT | |
| SCHEMBL26922834 | 0.65 | KMT2A (0.46) | KMT2A | |
| SCHEMBL8365979 | 0.64 | ALDH1A1 (0.67) | OPRM1TACR1POLBOPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2341967-A1 | INHALER WITH INDEXING LINKED TO MOVEMENT OF COVER | AstraZeneca AB (SE) | 2011-07-13 | — | — | EP | disclosed |