Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8333396 | 0.78 | TACR1 (0.54) | TACR1HSD11B1 | |
| SCHEMBL373753 | 0.73 | TACR1 (0.46) | TACR1HSD11B1SLC6A4SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL8331548 | 0.72 | TACR1 (0.45) | TACR1HSD11B1SLC6A4SMN1; SMN2LMNA | |
| SCHEMBL14347735 | 0.67 | ALDH1A1 (0.42) | HSD11B1SLC6A4SMN1; SMN2SLC6A2SLC6A3 | |
| SCHEMBL5571567 | 0.66 | P2RX7 (0.56) | TACR1P2RX7SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL31417144 | 0.66 | MAOA (0.53) | HSD11B1P2RX7SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2190767 | 0.65 | TP53 (0.42) | TACR1P2RX7SMN1; SMN2LMNAKMT2A | |
| SCHEMBL14347748 | 0.65 | SLC6A4 (0.41) | P2RX7SLC6A4SMN1; SMN2SLC6A2SLC6A3 | |
| SCHEMBL13059781 | 0.65 | KCNA3 (0.54) | TACR1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL13059779 | 0.64 | CYP3A4 (0.56) | HSD11B1MEN1KMT2AMAPK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050248-A1 | SUBSTITUTED PIPERIDINO-DIHYDROTHIENOPYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |