SCHEMBL2190913

SCHEMBL2190913

Cc1cc(C2(c3cc(C)c(O)c(C=O)c3)CCC(C(C)(C)C3CCC(c4cc(C)c(O)c(C=O)c4)(c4cc(C)c(O)c(C=O)c4)CC3)CC2)cc(C=O)c1O

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.43
ERN1 O75460 4/20 0.37
ESR1 P03372 2/20 0.32
ESR2 Q92731 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12419956 0.91 ERN1 (0.42) ACHEERN1
SCHEMBL13559715 0.91 ERN1 (0.42) ACHEERN1
SCHEMBL13518943 0.86 ACHE (0.47) ACHEERN1ESR1ESR2
SCHEMBL28308729 0.85 ACHE (0.58) ACHEESR1ESR2
SCHEMBL13519069 0.84 ACHE (0.55) ACHEERN1ESR1ESR2
SCHEMBL13518911 0.82 ACHE (0.44) ACHEERN1ESR1ESR2
SCHEMBL17435979 0.82 ACHE (0.41) ACHEERN1ESR1ESR2
SCHEMBL2192005 0.78 CD69 (0.36)
SCHEMBL2190883 0.77 ACHE (0.44) ACHEESR1ESR2
SCHEMBL9073417 0.76 ACHE (0.58) ACHEESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9522868-B2 Tetrakis(ether-substituted formylphenyl) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2016-12-20 US disclosed
US-9522868-B2 Tetrakis(ether-substituted formylphenyl) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2016-12-20 US disclosed
US-20160016884-A1 NEW TETRAKIS(ETHER-SUBSTITUTED FORMYLPHENYL) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2016-01-21 US disclosed
US-20160016884-A1 NEW TETRAKIS(ETHER-SUBSTITUTED FORMYLPHENYL) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2016-01-21 US disclosed
US-8921613-B2 Polynuclear poly(phenol) family HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2014-12-30 US disclosed
US-8921613-B2 Polynuclear poly(phenol) family HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2014-12-30 US disclosed
US-20120277479-A1 NOVEL POLYNUCLEAR POLY(PHENOL) FAMILY HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2012-11-01 US disclosed
US-20120277479-A1 NOVEL POLYNUCLEAR POLY(PHENOL) FAMILY HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2012-11-01 US disclosed
US-8278022-B2 Positive resist composition and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2012-10-02 US disclosed
US-8278022-B2 Positive resist composition and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2012-10-02 US disclosed
US-20110172457-A1 TETRAKIS(ETHER-SUBSTITUTED FORMYLPHENYL) AND NEW POLYNUCLEAR POLYPHENOL DERIVED FROM THE SAME HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2011-07-14 US disclosed
US-20110172457-A1 TETRAKIS(ETHER-SUBSTITUTED FORMYLPHENYL) AND NEW POLYNUCLEAR POLYPHENOL DERIVED FROM THE SAME HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2011-07-14 US disclosed
US-20090317745-A1 POSITIVE RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN TOKYO OHKA KOGYO CO., LTD (JP) 2009-12-24 US disclosed
US-20090317745-A1 POSITIVE RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN TOKYO OHKA KOGYO CO., LTD (JP) 2009-12-24 US disclosed
WO-2009154291-A1 NOVEL TETRAKIS(ETHER-SUBSTITUTED FORMYLPHENYL) AND NOVEL POLYNUCLEAR POLY(PHENOL) DERIVED FROM THE SAME 本州化学工業株式会社 (JP) 2009-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160016884-A1 NEW TETRAKIS(ETHER-SUBSTITUTED FORMYLPHENYL) AHR, PAH, ALK ACHE 4873/4885ERN1 2182/4885ESR1 502/4885
US-20120277479-A1 NOVEL POLYNUCLEAR POLY(PHENOL) FAMILY PAH, C1S, AP1S1 ACHE 3989/4885ERN1 2432/4885ESR1 875/4885
US-20110172457-A1 TETRAKIS(ETHER-SUBSTITUTED FORMYLPHENYL) AND NEW POLYNUCLEAR POLYPHENOL DERIVED FROM THE SAME AHR, PAH, ARNT ACHE 4301/4885ERN1 3527/4885ESR1 541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.