Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.52 |
| ▸ | NPC1 | O15118 | 8/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681499 | 0.86 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2FLT3MAPT | |
| SCHEMBL10187028 | 0.82 | SMN1; SMN2 (0.52) | RAB9ANPC1SMN1; SMN2FLT3MAPT | |
| SCHEMBL6195935 | 0.80 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2FLT3MAPT | |
| SCHEMBL2187619 | 0.79 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL6632697 | 0.78 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL10187027 | 0.76 | SMN1; SMN2 (0.51) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL21376322 | 0.75 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2FLT3MAPT | |
| SCHEMBL6198600 | 0.73 | NPC1 (0.64) | RAB9ANPC1SMN1; SMN2FLT3MAPT | |
| SCHEMBL3206132 | 0.69 | GSR (0.53) | RAB9ANPC1KDM4EALDH1A1KMT2A | |
| SCHEMBL1160454 | 0.68 | NPC1 (0.49) | RAB9ANPC1SMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626240-A1 | PROCESS OF PREPARATION OF A N-ARYL BENZYL SULFONAMIDE SUBSTITUTED WITH AN AMIDO GROUP | StemSynergy Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |