SCHEMBL2191063

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1345856	0.85	PARP1 (0.50)	PARP1KDM4EGPR84CHEK1IDO1
	SCHEMBL29798728	0.85	PARP1 (0.50)	PARP1KDM4EGPR84CHEK1IDO1
	SCHEMBL8622177	0.79	ACVR1 (0.46)	PARP1CHEK1ALDH1A1HTTKMT2A
	SCHEMBL1584889	0.79	PIM1 (0.56)	GPR84CHEK1ALDH1A1HTTIDO1
	SCHEMBL8700858	0.78	PARP1 (0.54)	PARP1KDM4EALDH1A1CYP2C19
	SCHEMBL2191001	0.78	PARP1 (0.54)	PARP1GPR84CHEK1ALDH1A1GAA
	SCHEMBL2574527	0.78	LMNA (0.57)	PARP1KDM4EALDH1A1GLAGAA
	SCHEMBL216175	0.78	PARP1 (0.54)	PARP1CHEK1ALDH1A1HTTIDO1
	SCHEMBL1507612	0.78	PARP1 (0.54)	PARP1KDM4ECHEK1ALDH1A1IDO1
	SCHEMBL3429702	0.77	MAPT (0.43)	PARP1GPR84CHEK1MPOALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.