SCHEMBL21916633

SCHEMBL21916633

COC(C(C)=O)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6932001 0.79 SLC1A3 (0.36) ACHE
SCHEMBL6931998 0.79 SLC1A3 (0.36) ACHE
SCHEMBL9196637 0.79 SLC1A3 (0.36) ACHE
SCHEMBL8600469 0.77 ACHE (0.45) ALDH1A1ACHE
SCHEMBL9162000 0.77 ACHE (0.31) ACHE
SCHEMBL21881710 0.77 ACHE (0.31) ACHE
SCHEMBL6289513 0.77 ACHE (0.31) ACHE
SCHEMBL1785886 0.76 ALDH1A1 (0.33) ALDH1A1
SCHEMBL15505327 0.76 ALDH1A1 (0.33) ALDH1A1
SCHEMBL23136604 0.75 TSHR (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023083381-A1 BISPECIFIC ANTIBODY-CAMPTOTHECIN DRUG CONJUGATE AND PHARMACEUTICAL USE THEREOF 成都百利多特生物药业有限责任公司 2023-05-19 WO disclosed
EP-3981434-A1 ANTI-B7-H4 ANTIBODY-DRUG CONJUGATE AND MEDICINAL USE THEREOF Shanghai Hansoh Biomedical Co., Ltd. (CN) 2022-04-13 EP disclosed
WO-2020244657-A1 ANTI-B7-H4 ANTIBODY–DRUG CONJUGATE AND MEDICINAL USE THEREOF 上海翰森生物医药科技有限公司 2020-12-10 WO disclosed
WO-2020063676-A1 LIGAND-DRUG CONJUGATE OF EXATECAN ANALOGUE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 江苏恒瑞医药股份有限公司 2020-04-02 WO disclosed