Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21916633 | 0.77 | ALDH1A1 (0.32) | ACHE | |
| SCHEMBL6931998 | 0.77 | SLC1A3 (0.36) | ACHE | |
| SCHEMBL6932001 | 0.77 | SLC1A3 (0.36) | ACHE | |
| SCHEMBL9196637 | 0.77 | SLC1A3 (0.36) | ACHE | |
| SCHEMBL9300841 | 0.76 | TSHR (0.39) | — | |
| SCHEMBL6289513 | 0.75 | ACHE (0.31) | ACHE | |
| SCHEMBL8600469 | 0.75 | ACHE (0.45) | ACHE | |
| SCHEMBL21881710 | 0.75 | ACHE (0.31) | ACHE | |
| SCHEMBL8600304 | 0.70 | ALDH1A1 (0.39) | ACHE | |
| SCHEMBL15094167 | 0.69 | ACHE (0.41) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2036177-A | — | — | None | — | — | JP | disclosed |
| EP-0347066-B1 | New enantiomers and their isolation | LUNDBECK & CO AS H (DK) | 1995-03-15 | — | — | EP | disclosed |
| US-RE34712-E | Pharmaceutically useful (+)-1-(3-dimethylaminopropyl)-1-(4'-fluorophenyl)-1,3-dihydroiso benzofuran-5-carbonitrile and non-toxic acid addition salts thereof | H. LUNDBECK A/S (DK) | 1994-08-30 | — | — | US | disclosed |
| US-4943590-A | ANTIDEPRESSANTS, STEREOSPECIFIC SYNTHESIS | H. LUNDBECK A/S (DK) | 1990-07-24 | — | — | US | disclosed |
| JP-H0236177-A | NEW ENANTIOMER AND METHOD FOR ISOLATING IT | H LUNDBECK AS | 1990-02-06 | — | — | JP | disclosed |
| EP-0340153-A1 | N-substituted imidazoles, process for their preparation and their use in medicaments | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-11-02 | — | — | EP | disclosed |