Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600304 | 0.79 | ALDH1A1 (0.39) | ACHESMN1; SMN2KMT2AALDH1A1HTT | |
| SCHEMBL8597614 | 0.78 | ACHE (0.44) | ACHESMN1; SMN2CA1CA2KMT2A | |
| SCHEMBL15094167 | 0.78 | ACHE (0.41) | ACHESMN1; SMN2CA1CA2KMT2A | |
| SCHEMBL9196637 | 0.77 | SLC1A3 (0.36) | ACHE | |
| SCHEMBL6932001 | 0.77 | SLC1A3 (0.36) | ACHE | |
| SCHEMBL21916633 | 0.77 | ALDH1A1 (0.32) | ACHEALDH1A1 | |
| SCHEMBL6931998 | 0.77 | SLC1A3 (0.36) | ACHE | |
| SCHEMBL8595237 | 0.76 | HCAR2 (0.34) | ACHECA1CA2ALDH1A1 | |
| SCHEMBL21881710 | 0.75 | ACHE (0.31) | ACHE | |
| SCHEMBL6289513 | 0.75 | ACHE (0.31) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592669-B1 | OPTICALLY ACTIVE TRIFLUOROLACTIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5665270-A | Optically active trifluorolactic acid derivative and liquid crystal composition | CHISSO CORPORATION (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0592669-A1 | OPTICALLY ACTIVE TRIFLUOROLACTIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1994-04-20 | — | — | EP | disclosed |