Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.56 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.56 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2193530 | 0.83 | SETD7 (0.48) | SETD7EHMT2ALDH1A1MEN1POLB | |
| SCHEMBL2196761 | 0.81 | SETD7 (0.81) | SETD7EHMT2RORCNPC1ALDH1A1 | |
| SCHEMBL2192050 | 0.79 | ALDH1A1 (0.55) | SETD7EHMT2SMN1; SMN2NPC1CYP2C9 | |
| SCHEMBL2196465 | 0.78 | SETD7 (0.51) | SETD7EHMT2RORCASH1L | |
| SCHEMBL2192864 | 0.78 | SETD7 (0.68) | SETD7EHMT2RORCPOLBMAPT | |
| SCHEMBL2192654 | 0.76 | SMN1; SMN2 (0.45) | SETD7EHMT2SMN1; SMN2NPC1CYP2C9 | |
| SCHEMBL2192171 | 0.76 | SETD7 (0.60) | SETD7EHMT2RORCNPC1ALDH1A1 | |
| SCHEMBL2194262 | 0.74 | SETD7 (0.48) | SETD7EHMT2RORCALDH1A1ASH1L | |
| SCHEMBL12581571 | 0.73 | APEX1 (0.65) | ACMSDSMN1; SMN2NPC1APEX1CYP2C9 | |
| SCHEMBL3889076 | 0.73 | APEX1 (0.65) | ACMSDSMN1; SMN2APEX1CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011082098-A1 | LYSINE AND ARGININE METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | THE ROCKEFELLER UNIVERSITY (US) | 2011-07-07 | — | — | WO | disclosed |