Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.55 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.55 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2191641 | 0.93 | SETD7 (0.58) | SETD7EHMT2ALDH1A1KDM4EKDM4C | |
| SCHEMBL2193598 | 0.83 | SETD7 (0.61) | SETD7EHMT2ALDH1A1KDM4EKDM4C | |
| SCHEMBL2192864 | 0.81 | SETD7 (0.68) | SETD7EHMT2PPARGRORCPOLB | |
| SCHEMBL2192171 | 0.81 | SETD7 (0.60) | SETD7EHMT2ALDH1A1RORCDHODH | |
| SCHEMBL2196761 | 0.80 | SETD7 (0.81) | SETD7EHMT2ALDH1A1KDM4ERORC | |
| SCHEMBL2193530 | 0.78 | SETD7 (0.48) | SETD7EHMT2HNF4AALDH1A1POLB | |
| SCHEMBL2196465 | 0.77 | SETD7 (0.51) | SETD7EHMT2RORCHSD17B10DHODH | |
| SCHEMBL12492330 | 0.77 | SETD7 (0.66) | SETD7EHMT2PPARGDHODH | |
| SCHEMBL2192050 | 0.74 | ALDH1A1 (0.55) | SETD7EHMT2ALDH1A1KDM4ELMNA | |
| SCHEMBL4101633 | 0.74 | KDM4E (0.63) | ALDH1A1KDM4ELMNASMN1; SMN2KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011082098-A1 | LYSINE AND ARGININE METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | THE ROCKEFELLER UNIVERSITY (US) | 2011-07-07 | — | — | WO | disclosed |