Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19527210 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAHTTCA12CA1 | |
| SCHEMBL13741500 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNAHTTCA12CA1 | |
| SCHEMBL18002248 | 0.86 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAHTTCA12CA1 | |
| SCHEMBL292365 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAHTTCA12CA1 | |
| SCHEMBL15677565 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAHTTCA12CA1 | |
| SCHEMBL291124 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAHTTCA12CA1 | |
| SCHEMBL30757524 | 0.84 | CTSS (0.52) | SMN1; SMN2LMNAHTTCTSLCTSB | |
| SCHEMBL12921003 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAHTTCA12CA1 | |
| SCHEMBL21985416 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAHTTCA12CA1 | |
| SCHEMBL292084 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAHTTL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250034201-A1 | PRODRUGS OF GANAXOLONE | IMMEDICA PHARMA US INC. | 2025-01-30 | — | — | US | disclosed |
| EP-4493574-A1 | PRODRUGS OF GANAXOLONE | Marinus Pharmaceuticals, Inc. (US) | 2025-01-22 | — | — | EP | disclosed |
| WO-2023178299-A1 | PRODRUGS OF GANAXOLONE | MARINUS PHARMACEUTICALS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| WO-2023178299-A1 | PRODRUGS OF GANAXOLONE | MARINUS PHARMACEUTICALS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| CN-115650984-A | Preparation method of anagliptin | 江苏君若药业有限公司 | 2023-01-31 | — | — | CN | disclosed |
| US-9708245-B2 | Fatty acid acylated salicylates and their uses | CATABASIS PHARMACEUTICALS, INC. (US) | 2017-07-18 | — | — | US | disclosed |
| US-9708245-B2 | Fatty acid acylated salicylates and their uses | CATABASIS PHARMACEUTICALS, INC. (US) | 2017-07-18 | — | — | US | disclosed |
| US-9708245-B2 | Fatty acid acylated salicylates and their uses | CATABASIS PHARMACEUTICALS, INC. (US) | 2017-07-18 | — | — | US | disclosed |
| EP-2521447-B1 | FATTY ACID FUMARATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS INC (US) | 2017-06-14 | — | — | EP | disclosed |
| US-20160340294-A1 | FATTY ACID FUMARATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. | 2016-11-24 | — | — | US | disclosed |
| EP-1677599-A1 | HYDROXY PYRIDOPYRROLOPYRAZINE DIONE COMPOUNDS USEFUL AS HIV INTEGRASE INHIBITORS | Merck & Co., Inc. (US) | 2006-07-12 | — | — | EP | disclosed |
| EP-1544208-A1 | PYRAZOLE DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, MEDICINAL USE THEREOF, AND INTERMEDIATE FOR PRODUCTION THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2005-06-22 | — | — | EP | disclosed |
| WO-2005041664-A1 | HYDROXY PYRIDOPYRROLOPYRAZINE DIONE COMPOUNDS USEFUL AS HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 2005-05-12 | — | — | WO | disclosed |
| US-5661146-A | ANALGESICS | G.D. SEARLE & CO. (US) | 1997-08-26 | — | — | US | disclosed |
| US-5504077-A | ANALGESICS | G. D. SEARLE & CO. (US) | 1996-04-02 | — | — | US | disclosed |
| WO-1995033734-A1 | SUBSTITUTED DIBENZOXAZEPINE AND DIBENZTHIAZEPINE CARBAMATES USEFUL AS PROSTAGLANDIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1995-12-14 | — | — | WO | disclosed |
| US-5449675-A | Analgesics | G. D. SEARLE & CO. (US) | 1995-09-12 | — | — | US | disclosed |
| US-5441950-A | Analgesics, prostaglandin E2 antagonists | G. D. SEARLE & CO. (US) | 1995-08-15 | — | — | US | disclosed |
| WO-1995016675-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-06-22 | — | — | WO | disclosed |
| US-5364850-A | Analgesics | G. D. SEARLE & CO. (US) | 1994-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250034201-A1 | PRODRUGS OF GANAXOLONE | CYP21A2, CYP11B1, CYP11B2 | SMN1; SMN2 2734/4885LMNA 1747/4885HTT 3122/4885 |
| US-20160340294-A1 | FATTY ACID FUMARATE DERIVATIVES AND THEIR USES | FH, FASN, ELOVL1 | SMN1; SMN2 377/4885LMNA 2735/4885HTT 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.