Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 3/20 | 0.57 |
| ▸ | IL1RN | P18510 | 7/20 | 0.56 |
| ▸ | ERAP2 | Q6P179 | 7/20 | 0.56 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 8/20 | 0.54 |
| ▸ | MMP9 | P14780 | 6/20 | 0.54 |
| ▸ | MMP8 | P22894 | 6/20 | 0.54 |
| ▸ | MMP1 | P03956 | 3/20 | 0.54 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.52 |
| ▸ | ADAM12 | O43184 | 1/20 | 0.52 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MMP7 | P09237 | 1/20 | 0.52 |
| ▸ | MMP12 | P39900 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | MMP14 | P50281 | 1/20 | 0.52 |
| ▸ | MMP15 | P51511 | 1/20 | 0.52 |
| ▸ | MMP16 | P51512 | 1/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2184049 | 0.83 | ERAP2 (0.58) | IL1RNERAP2ERAP1MMP2MMP9 | |
| SCHEMBL2194704 | 0.83 | IL1RN (0.55) | KISS1RIL1RNERAP2ERAP1ECE1 | |
| SCHEMBL11663890 | 0.82 | CCKBR (0.51) | KISS1RIL1RNERAP2ERAP1 | |
| SCHEMBL31696723 | 0.82 | ACE (0.60) | KISS1RERAP2ECE1 | |
| SCHEMBL2193237 | 0.81 | GHSR (0.61) | MMP2MMP9MMP8MMP1 | |
| SCHEMBL9822631 | 0.81 | ECE1 (0.70) | IL1RNERAP2ERAP1MMP2MMP9 | |
| SCHEMBL4959976 | 0.81 | ERAP2 (0.75) | IL1RNERAP2ERAP1ECE1 | |
| SCHEMBL4959992 | 0.81 | ERAP2 (0.75) | IL1RNERAP2ERAP1ECE1 | |
| SCHEMBL30051783 | 0.81 | ECE1 (0.70) | IL1RNERAP2ERAP1MMP2MMP9 | |
| SCHEMBL3979342 | 0.81 | ERAP2 (0.62) | KISS1RIL1RNERAP2ERAP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682153-B2 | Polymer conjugates of therapeutic peptides | NEKTAR THERAPEUTICS (US) | 2017-06-20 | — | — | US | disclosed |
| US-20160022828-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS | 2016-01-28 | — | — | US | disclosed |
| US-20110171312-A1 | MODIFIED THERAPEUTIC PEPTIDES, METHODS OF THEIR PREPARATION AND USE | NEKTAR THERAPEUTICS (US) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160022828-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | KISS1R 1433/4885IL1RN 546/4885ERAP2 638/4885 |
| US-20110171312-A1 | MODIFIED THERAPEUTIC PEPTIDES, METHODS OF THEIR PREPARATION AND USE | DNPEP, VIP, PTMS | KISS1R 1880/4885IL1RN 323/4885ERAP2 697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.