Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 17/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21922388 | 0.83 | ENPP2 (0.42) | ENPP2GAA | |
| SCHEMBL22186143 | 0.80 | ALDH1A1 (0.30) | — | |
| SCHEMBL2093848 | 0.75 | ENPP2 (0.40) | ENPP2 | |
| SCHEMBL26581171 | 0.75 | MAOB (0.41) | GAA | |
| SCHEMBL21922387 | 0.74 | ENPP2 (0.51) | ENPP2 | |
| SCHEMBL21503604 | 0.74 | SCN10A (0.36) | ENPP2 | |
| SCHEMBL21922352 | 0.74 | GAA (0.53) | GAA | |
| SCHEMBL2093843 | 0.72 | ENPP2 (0.38) | ENPP2 | |
| SCHEMBL12949847 | 0.72 | RXRA (0.39) | ENPP2 | |
| SCHEMBL13548218 | 0.71 | HTT (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200131151-A1 | NOVEL PYRIDAZINES | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131151-A1 | NOVEL PYRIDAZINES | ENPP2, PLPBP, PRDX6 | ENPP2 1/4885GAA 1248/4885HDAC1 2222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.