SCHEMBL21925560

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Bicarbonate SCHEMBL21925561	0.78	GPR3 (0.44)	MAPTGPR3KMT2AKCNA5NPC1
	SCHEMBL6502792	0.77	KMT2A (0.47)	MAPTGPR3CA1CA2KMT2A
	SCHEMBL17456836	0.73	GPR3 (0.44)	MAPTGPR3KMT2AALDH1A1POLB
	SCHEMBL31355068	0.72	GPR3 (0.41)	MAPTGPR3KMT2APOLB
	SCHEMBL4600049	0.72	GPR3 (0.41)	MAPTGPR3KMT2APOLB
	SCHEMBL4600752	0.72	CTRB1 (0.40)	MAPTALDH1A1NPC1
	SCHEMBL5407004	0.72	CTRB1 (0.40)	MAPTALDH1A1NPC1
	SCHEMBL4600067	0.72	CTRB1 (0.40)	MAPTALDH1A1NPC1
	SCHEMBL30510366	0.72	CTRB1 (0.40)	MAPTALDH1A1NPC1
	SCHEMBL3202976	0.71	KMT2A (0.40)	MAPTGPR3KMT2APOLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.