SCHEMBL219269

SCHEMBL219269

C=C(C)C(=O)OC(CC)S(=O)(=O)O.[NaH]

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
ALDH1A1 P00352 2/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14981 0.98 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL444304 0.96 TSHR (0.37) TSHRALDH1A1THRB
Acrylic Acid SCHEMBL27993035 0.89 TSHR (0.33) TSHRALDH1A1THRB
SCHEMBL5918586 0.86 TSHR (0.31) TSHR
SCHEMBL5872177 0.85 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL483980 0.84 ALDH1A1 (0.39) TSHRALDH1A1THRB
SCHEMBL11440456 0.83 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL5176837 0.83 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL10490314 0.83 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL15054110 0.82 TSHR (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11866588-B2 Polymerizable near-IR dyes PROFUSA, INC. (US) 2024-01-09 US claimed
US-20200140690-A1 POLYMERIZABLE NEAR-IR DYES PROFUSA, INC. (US) 2020-05-07 US claimed
EP-3558118-A1 POLYMERIZABLE NEAR-IR DYES Profusa, Inc. (US) 2019-10-30 EP claimed
WO-2018119204-A1 POLYMERIZABLE NEAR-IR DYES PROFUSA, INC. (US) 2018-06-28 WO claimed
US-8394357-B2 Optical determination of glucose utilizing boronic acid adducts THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-03-12 US claimed
EP-1960779-B1 OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS-II UNIV CALIFORNIA (US) 2010-08-25 EP claimed
EP-2147003-A1 PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS Glumetrics, Inc. (US) 2010-01-27 EP claimed
US-20090148344-A1 OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS SINGARAM BAKTHAN 2009-06-11 US claimed
US-7470420-B2 Optical determination of glucose utilizing boronic acid adducts THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-12-30 US claimed
US-20080305009-A1 PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS GLUMETRICS INC. (US) 2008-12-11 US claimed
WO-2008137604-A1 PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS GLUMETRICS, INC. (US) 2008-11-13 WO claimed
EP-1960779-A2 OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS-II The Regents of the University of California (US) 2008-08-27 EP claimed
WO-2007067743-A2 OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS-II THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-06-14 WO claimed
US-20060083688-A1 Optical determination of glucose utilizing boronic acid adducts THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-04-20 US claimed
US-4792527-A Method of assaying biologically active substances and labelling agents therefor TORAY INDUSTRIES, INC. (JP) 1988-12-20 US claimed
US-3943223-A Method of manufacturing acrylic fibers KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-03-09 US claimed
EP-3838588-B2 GAS BARRIER LAMINATE AND METHOD FOR PRODUCING SAME OJI HOLDINGS CORP (JP) 2026-04-22 EP disclosed
EP-4660371-A1 HEAT SEAL PAPER Oji Holdings Corporation (JP) 2025-12-10 EP disclosed
US-4002809-A Method of manufacturing acrylic fibers KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1977-01-11 US disclosed
US-3937802-A SPRAYABLE HAIR-SETTING COMPOSITION CONTAINING A SULFONATE CONTAINING HYDROPHILIC COPOLYMER SANYO CHEMICAL INDUSTRIES, LTD. (JA) 1976-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080305009-A1 PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS BLVRB, PDXK, PNPO TSHR 2859/4885ALDH1A1 2649/4885THRB 1727/4885
US-20060083688-A1 Optical determination of glucose utilizing boronic acid adducts NISCH, FOSB, BLVRB TSHR 3235/4885ALDH1A1 1006/4885THRB 1972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.