Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30645390 | 0.89 | KDM4E (0.39) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL16815262 | 0.81 | KDM4E (0.45) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL747872 | 0.81 | MAPT (0.45) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL747873 | 0.81 | MAPT (0.45) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL4417223 | 0.81 | MAPT (0.45) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL31037760 | 0.80 | TGFBR1 (0.42) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL2879599 | 0.79 | KDM4E (0.44) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Hydrogen Sulfide SCHEMBL28147035 | 0.79 | MAPT (0.44) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Hydrogen Sulfide SCHEMBL27945862 | 0.79 | MAPT (0.44) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL2358774 | 0.79 | KDM4E (0.44) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111201017-A | Methods for preparing deuterium-enriched N-acetylcysteine amide (D-NACA) and (2R,2R ') -3,3' -disulfanediylbis (2-acetamidopropionamide) (DINACA) and for treating diseases involving oxidative stress using D-NACA and DINACA | 纳崔泰制药有限公司 | 2020-05-26 | — | — | CN | disclosed |
| EP-3313525-A1 | ANTIBODY DRUG CONJUGATES OF KINESIN SPINDEL PROTEIN (KSP) INHIBITORS WITH ANTI-B7H3-ANTIBODIES | Bayer Pharma Aktiengesellschaft (DE) | 2018-05-02 | — | — | EP | disclosed |
| WO-2016207103-A1 | ANTIBODY DRUG CONJUGATES OF KINESIN SPINDEL PROTEIN (KSP) INHIBITORS WITH ANTI-B7H3-ANTIBODIES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-29 | — | — | WO | disclosed |
| US-20160022620-A1 | ENCAPSULATED COMPOSITION FOR BINDING ALDEHYDES IN THE STOMACH | BIOHIT OYJ (FI) | 2016-01-28 | — | — | US | disclosed |
| WO-2015189479-A1 | COMPOSITION CONTAINING CYSTEINE OR A DERIVATIVE THEREOF FOR THE TREATMENT OR PREVENTION OF ACUTE HYPERSENSITIVITIES | BIOHIT OYJ (FI) | 2015-12-17 | — | — | WO | disclosed |
| WO-2014140411-A1 | ENCAPSULATED COMPOSITION FOR BINDING ALDEHYDES IN THE STOMACH | BIOHIT OYJ (FI) | 2014-09-18 | — | — | WO | disclosed |
| US-20110171296-A1 | METHOD AND PREPARATION FOR BINDING ACETALDEHYDE IN SALIVA, THE STOMACH AND THE LARGE INTESTINE | BIOHIT OYJ (FI) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171296-A1 | METHOD AND PREPARATION FOR BINDING ACETALDEHYDE IN SALIVA, THE STOMACH AND THE LARGE INTESTINE | SI, ADH1C, ADH1A | KDM4E 4713/4885MAPT 3706/4885THRB 2688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.