SCHEMBL219295

SCHEMBL219295

OC(CCl)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.58
KDM4E B2RXH2 2/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
AOC3 Q16853 5/20 0.52
RIPK1 Q13546 1/20 0.48
BCAT2 O15382 1/20 0.45
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TSHR P16473 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL316028 1.00 LMNA (0.58) LMNAKDM4EL3MBTL1AOC3RIPK1
SCHEMBL932391 1.00 LMNA (0.58) LMNAKDM4EL3MBTL1AOC3RIPK1
SCHEMBL6487259 0.86 LMNA (0.47) LMNAKDM4EL3MBTL1AOC3
SCHEMBL1142222 0.80 RIPK1 (0.55) LMNAKDM4EL3MBTL1AOC3RIPK1
SCHEMBL1200943 0.80 RIPK1 (0.55) LMNAKDM4EL3MBTL1AOC3RIPK1
SCHEMBL525669 0.80 RIPK1 (0.55) LMNAKDM4EL3MBTL1AOC3RIPK1
SCHEMBL29926486 0.80 RIPK1 (0.55) LMNAKDM4EL3MBTL1AOC3RIPK1
SCHEMBL10799093 0.79 TAAR1 (0.39) LMNAKDM4EL3MBTL1AOC3SMN1; SMN2
SCHEMBL30716448 0.78 RIPK1 (0.53) LMNAKDM4EL3MBTL1AOC3RIPK1
Phenylpropanol SCHEMBL28598207 0.78 LMNA (0.86) LMNAKDM4EL3MBTL1AOC3RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 692 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116813666-A Phosphine ligand compound with benzyl alcohol group and preparation method and application thereof 中国石油化工股份有限公司 2023-09-29 CN claimed
CN-110872234-B Synthesis method of (1R) -2- [ [ [2- (4-nitrophenyl) ethyl ] amino ] methyl ] benzyl alcohol hydrochloride 苏州永健生物医药有限公司 2022-03-04 CN claimed
CN-111187216-A Method for synthesizing imidazole ethanol by continuous method 徐州工业职业技术学院 2020-05-22 CN claimed
CN-110872234-A Synthesis method of (1R) -2- [ [ [2- (4-nitrophenyl) ethyl ] amino ] methyl ] benzyl alcohol hydrochloride 苏州永健生物医药有限公司 2020-03-10 CN claimed
CN-105063103-A Method for producing chiral phenyl dichloroethanol with molds UNIV QINGDAO SCIENCE & TECHNOLOGY 2015-11-18 CN claimed
CN-104745556-A Recombinant halohydrin dehalogenase, and mutant and engineering strain and applications thereof UNIV ZHEJIANG TECHNOLOGY 2015-07-01 CN claimed
CN-104357468-A Parvibaculum lavamentivorans ZJB 14001, halohydrin dehalogenase enzyme gene, enzyme, engineered bacterium and application UNIV ZHEJIANG TECHNOLOGY 2015-02-18 CN claimed
CN-104263713-A Tistrella mobilis, halohydrin dehalogenase, gene, vector, recombinant strain and application of halohydrin dehalogenase UNIV ZHEJIANG TECHNOLOGY 2015-01-07 CN claimed
CN-101503714-A Method for asymmetric synthesis of (S)-2-chloro-1-phenylethanol derivative UNIV GUANGDONG TECHNOLOGY (CN) 2009-08-12 CN claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
EP-0507278-A2 Immobilised biocatalyser, its preparation and use for ester synthesis in a column reactor HOECHST AKTIENGESELLSCHAFT (DE) 1992-10-07 EP claimed
EP-0288994-B1 PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS Chisso Corporation (JP) 1992-07-22 EP claimed
US-4996158-A Optical resolution of racemic alcohols LION CORPORATION, 3-7, HONJO 1-CHOME, SUMIDA-KU, TOKYO, JAPAN 1991-02-26 US claimed
US-4962031-A SPECIFIC COMPOUNDS HAVING HYDROXYL GROUPS REACTED WITH ESTERS IN PRESENCE OF HYDROLASES CHISSO CORPORATION (JP) 1990-10-09 US claimed
EP-0288994-A2 Process for producing optically active compounds Chisso Corporation (JP) 1988-11-02 EP claimed
JP-56092282-A None JP disclosed
EP-4599931-A1 A DRUG COMPRISING A RADICAL GENERATING CATALYST Acenet Inc. (JP) 2025-08-13 EP disclosed
US-4174228-A SPRAYABLE FIREPROOFING MATERIAL PPG INDUSTRIES, INC. (US) 1979-11-13 US disclosed
US-4024193-A Homogeneous hydrogenation process ICI UNITED STATES INC. (US) 1977-05-17 US disclosed