Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.52 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL219295 | 1.00 | LMNA (0.58) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL316028 | 1.00 | LMNA (0.58) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL6487259 | 0.86 | LMNA (0.47) | LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL1142222 | 0.80 | RIPK1 (0.55) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL1200943 | 0.80 | RIPK1 (0.55) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL525669 | 0.80 | RIPK1 (0.55) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL29926486 | 0.80 | RIPK1 (0.55) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL10799093 | 0.79 | TAAR1 (0.39) | LMNAKDM4EL3MBTL1AOC3SMN1; SMN2 | |
| SCHEMBL30716448 | 0.78 | RIPK1 (0.53) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Phenylpropanol SCHEMBL28598207 | 0.78 | LMNA (0.86) | LMNAKDM4EL3MBTL1AOC3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685248-B1 | OXIDOREDUCTASE FROM METSCHNIKOWIA ZOBELLII | IEP GMBH (DE) | 2010-06-09 | — | — | EP | claimed |
| EP-1685248-A2 | OXIDOREDUCTASE FROM METSCHNIKOWIA ZOBELLII | IEP GmbH (DE) | 2006-08-02 | — | — | EP | claimed |
| WO-2005049816-A2 | OXIDOREDUCTASE FROM METSCHNIKOWIA ZOBELLII | JUELICH ENZYME PRODUCTS GMBH (DE) | 2005-06-02 | — | — | WO | claimed |
| EP-0288994-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS | Chisso Corporation (JP) | 1992-07-22 | — | — | EP | claimed |
| US-4996158-A | Optical resolution of racemic alcohols | LION CORPORATION, 3-7, HONJO 1-CHOME, SUMIDA-KU, TOKYO, JAPAN | 1991-02-26 | — | — | US | claimed |
| US-4962031-A | SPECIFIC COMPOUNDS HAVING HYDROXYL GROUPS REACTED WITH ESTERS IN PRESENCE OF HYDROLASES | CHISSO CORPORATION (JP) | 1990-10-09 | — | — | US | claimed |
| EP-0288994-A2 | Process for producing optically active compounds | Chisso Corporation (JP) | 1988-11-02 | — | — | EP | claimed |
| CN-117821525-A | Enzymatic synthesis method of halohydrin medicine chiral building block | 宁波酶赛生物工程有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-111484986-B | Short-chain dehydrogenase and application thereof | 沈阳药科大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-114560892-A | Chiral tridentate nitrogen phosphine ligand synthesized based on ferrocene skeleton and application thereof | 广东工业大学 | 2022-05-31 | — | — | CN | disclosed |
| WO-2022074177-A1 | DYNAMIC KINETIC RESOLUTION OF ALCOHOLS BY ENANTIOSELECTIVE SILYLATION | Technische Universität Berlin (DE) | 2022-04-14 | — | — | WO | disclosed |
| EP-3981773-A1 | DYNAMIC KINETIC RESOLUTION OF ALCOHOLS BY ENANTIOSELECTIVE SILYLATION | Technische Universität Berlin (DE) | 2022-04-13 | — | — | EP | disclosed |
| CN-111484986-A | Short-chain dehydrogenase and application thereof | 沈阳药科大学 | 2020-08-04 | — | — | CN | disclosed |
| WO-1991000274-A1 | N-SUBSTITUTED CYCLOALKYL AND POLYCYCLOALKYL ALPHA-SUBSTITUTED TRP-PHE- AND PHENETHYLAMINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1991-01-10 | — | — | WO | disclosed |
| EP-0405537-A1 | N-substituted cycloalkyl and polycycloalkyl alpha-substituted Trp-Phe- and phenethylamine derivatives | WARNER-LAMBERT COMPANY (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4962031-A | SPECIFIC COMPOUNDS HAVING HYDROXYL GROUPS REACTED WITH ESTERS IN PRESENCE OF HYDROLASES | CHISSO CORPORATION (JP) | 1990-10-09 | — | — | US | disclosed |
| US-4943652-A | Process for asymmetrically reducing carbonyl compounds | AJINOMOTO CO., INC. (JP) | 1990-07-24 | — | — | US | disclosed |
| US-4857468-A | BIOSYNTHESIS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0320096-A1 | Process for asymmetrically reducing carbonyl compounds | AJINOMOTO CO., INC. (JP) | 1989-06-14 | — | — | EP | disclosed |
| EP-0288994-A2 | Process for producing optically active compounds | Chisso Corporation (JP) | 1988-11-02 | — | — | EP | disclosed |