Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.48 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.48 |
| ▸ | PTPRG | P23470 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.36 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2192050 | 0.85 | ALDH1A1 (0.55) | SETD7EHMT2RAB9AGAAKMT2A | |
| SCHEMBL2192071 | 0.83 | SETD7 (0.56) | SETD7EHMT2KMT2AMEN1HTT | |
| SCHEMBL2192654 | 0.81 | SMN1; SMN2 (0.45) | SETD7EHMT2RAB9AGAAKMT2A | |
| SCHEMBL2191641 | 0.80 | SETD7 (0.58) | SETD7EHMT2GAAKMT2AMEN1 | |
| SCHEMBL2196465 | 0.79 | SETD7 (0.51) | SETD7EHMT2CCR2DHODHHTR6 | |
| SCHEMBL2192976 | 0.78 | SETD7 (0.55) | SETD7EHMT2CCR2L3MBTL1MCL1 | |
| SCHEMBL2193598 | 0.75 | SETD7 (0.61) | SETD7EHMT2GAAMCL1ALDH1A1 | |
| SCHEMBL2194262 | 0.75 | SETD7 (0.48) | SETD7EHMT2CCR2DHODHALDH1A1 | |
| SCHEMBL2192864 | 0.74 | SETD7 (0.68) | SETD7EHMT2POLBMAPT | |
| SCHEMBL2196761 | 0.73 | SETD7 (0.81) | SETD7EHMT2RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011082098-A1 | LYSINE AND ARGININE METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | THE ROCKEFELLER UNIVERSITY (US) | 2011-07-07 | — | — | WO | disclosed |