Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21933023 | 0.88 | MAPT (0.50) | MEN1KMT2AMAPTTP53NPC1 | |
| SCHEMBL21933042 | 0.83 | ALOX15 (0.48) | MEN1KMT2ATP53NPC1POLB | |
| SCHEMBL21933031 | 0.81 | ABCG2 (0.54) | MEN1KMT2ANPC1POLBABCG2 | |
| SCHEMBL21933045 | 0.81 | ABCG2 (0.56) | MEN1KMT2AMAPTNPC1POLB | |
| SCHEMBL7267860 | 0.80 | MEN1 (0.65) | MEN1KMT2AMAPTTP53NPC1 | |
| SCHEMBL18264152 | 0.80 | MEN1 (0.56) | MEN1KMT2AMAPTTP53NPC1 | |
| SCHEMBL21933015 | 0.77 | NPY5R (0.51) | MEN1KMT2AMAPTTP53NPC1 | |
| SCHEMBL21933030 | 0.77 | GAA (0.54) | MEN1KMT2AMAPTTP53POLB | |
| SCHEMBL21933029 | 0.75 | ABCG2 (0.52) | MEN1KMT2AMAPTTP53NPC1 | |
| SCHEMBL21933024 | 0.75 | MAPT (0.53) | MEN1KMT2AMAPTTP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3876933-B1 | NEUTROPHIL INFLAMMATION INHIBITOR AND USES THEREOF | UNIV CHANG GUNG SCIENCE & TECHNOLOGY (TW) | 2023-09-13 | — | — | EP | disclosed |
| US-10654848-B1 | Neutrophil inflammation inhibitor and uses thereof | CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2020-05-19 | — | — | US | disclosed |
| US-20200148674-A1 | NEUTROPHIL INFLAMMATION INHIBITOR AND USES THEREOF | CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10654848-B1 | Neutrophil inflammation inhibitor and uses thereof | SERPINB1, SERPINE1, MMP8 | MEN1 4107/4885KMT2A 4847/4885MAPT 2111/4885 |
| US-20200148674-A1 | NEUTROPHIL INFLAMMATION INHIBITOR AND USES THEREOF | SERPINB1, SERPINE1, MMP8 | MEN1 4107/4885KMT2A 4847/4885MAPT 2111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.