Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 11/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.55 |
| ▸ | PDE5A | O76074 | 1/20 | 0.55 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.53 |
| ▸ | LTK | P29376 | 1/20 | 0.53 |
| ▸ | GRK5 | P34947 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | CDK8 | P49336 | 1/20 | 0.53 |
| ▸ | CDK7 | P50613 | 1/20 | 0.53 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.53 |
| ▸ | NEK4 | P51957 | 1/20 | 0.53 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.53 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.53 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21933040 | 0.87 | NPY5R (0.54) | ABCG2MEN1KMT2AABCB1HTT | |
| SCHEMBL21933042 | 0.84 | ALOX15 (0.48) | ABCG2MEN1KMT2APDE5AMAP4K4 | |
| SCHEMBL21933046 | 0.82 | POLB (0.56) | MEN1KMT2AHTTLMNANPC1 | |
| SCHEMBL21933022 | 0.81 | POLB (0.53) | ABCG2MEN1KMT2AEGFRHTT | |
| SCHEMBL21933016 | 0.81 | MEN1 (0.57) | ABCG2MEN1KMT2APDE5ALMNA | |
| SCHEMBL18264403 | 0.79 | BTK (0.57) | ABCG2MEN1KMT2AABCB1PDE5A | |
| SCHEMBL21933015 | 0.79 | NPY5R (0.51) | ABCG2MEN1KMT2ACLK4HTT | |
| SCHEMBL21933029 | 0.79 | ABCG2 (0.52) | ABCG2MEN1KMT2APDE5AEGFR | |
| SCHEMBL21933034 | 0.78 | ABCG2 (0.54) | ABCG2MEN1KMT2AABCB1PDE5A | |
| SCHEMBL2301864 | 0.78 | KDM4E (0.59) | ABCG2MEN1KMT2AABCB1PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3876933-B1 | NEUTROPHIL INFLAMMATION INHIBITOR AND USES THEREOF | UNIV CHANG GUNG SCIENCE & TECHNOLOGY (TW) | 2023-09-13 | — | — | EP | disclosed |
| US-10654848-B1 | Neutrophil inflammation inhibitor and uses thereof | CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2020-05-19 | — | — | US | disclosed |
| US-20200148674-A1 | NEUTROPHIL INFLAMMATION INHIBITOR AND USES THEREOF | CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10654848-B1 | Neutrophil inflammation inhibitor and uses thereof | SERPINB1, SERPINE1, MMP8 | ABCG2 3661/4885MEN1 4107/4885KMT2A 4847/4885 |
| US-20200148674-A1 | NEUTROPHIL INFLAMMATION INHIBITOR AND USES THEREOF | SERPINB1, SERPINE1, MMP8 | ABCG2 3661/4885MEN1 4107/4885KMT2A 4847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.