Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20034721 | 0.94 | SMN1; SMN2 (0.40) | TP53MEN1KMT2ACYP2C19HSD17B10 | |
| SCHEMBL10017830 | 0.92 | KMT2A (0.36) | TP53MEN1KMT2AHSD17B10HDAC3 | |
| SCHEMBL20034715 | 0.90 | CASP2 (0.42) | TP53MEN1KMT2ACASP2HDAC3 | |
| SCHEMBL17944164 | 0.89 | HDAC3 (0.37) | TP53MEN1KMT2ACYP2C19HSD17B10 | |
| SCHEMBL19698272 | 0.88 | HDAC3 (0.39) | TP53MEN1KMT2ACYP2C19HSD17B10 | |
| SCHEMBL26973040 | 0.87 | SMN1; SMN2 (0.42) | MEN1KMT2AHSD17B10SMN1; SMN2HPGD | |
| SCHEMBL17944136 | 0.86 | SIGMAR1 (0.38) | MEN1KMT2ACYP2C19HSD17B10HDAC3 | |
| SCHEMBL19703814 | 0.86 | HDAC3 (0.44) | TP53MEN1KMT2ACYP2C19HSD17B10 | |
| SCHEMBL20801345 | 0.86 | HDAC3 (0.42) | TP53MEN1KMT2ACYP2C19HSD17B10 | |
| SCHEMBL18120584 | 0.86 | SMN1; SMN2 (0.38) | TP53MEN1KMT2ACYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3250232-B1 | BRANCHED AND LINEAR CHIMERIC COMPOUNDS, POLYNUCLEOTIDES, USES AND METHODS FOR PREPARATION THEREOF | DYNAVAX TECH CORP (US) | 2020-04-29 | — | — | EP | disclosed |