Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21933100 | 0.92 | TP53 (0.39) | KMT2AALDH1A1MEN1POLBSMN1; SMN2 | |
| SCHEMBL17944136 | 0.88 | SIGMAR1 (0.38) | KMT2AGAAALDH1A1MEN1POLB | |
| SCHEMBL18120584 | 0.88 | SMN1; SMN2 (0.38) | KMT2AGAAALDH1A1MEN1POLB | |
| SCHEMBL20647310 | 0.87 | SMN1; SMN2 (0.41) | KMT2AGAAALDH1A1MEN1POLB | |
| SCHEMBL22702626 | 0.87 | SMN1; SMN2 (0.37) | GAAALDH1A1POLBSMN1; SMN2HPGD | |
| SCHEMBL20034721 | 0.86 | SMN1; SMN2 (0.40) | KMT2AALDH1A1MEN1SMN1; SMN2HPGD | |
| SCHEMBL21928974 | 0.86 | ALDH1A1 (0.34) | KMT2AGAAALDH1A1MEN1POLB | |
| SCHEMBL17944164 | 0.86 | HDAC3 (0.37) | KMT2AGAAALDH1A1MEN1POLB | |
| SCHEMBL20078656 | 0.86 | LMNA (0.42) | KMT2AALDH1A1MEN1POLBSMN1; SMN2 | |
| SCHEMBL20034715 | 0.85 | CASP2 (0.42) | KMT2AALDH1A1MEN1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120014975-A1 | MODIFIED SINGLE DOMAIN ANTIGEN BINDING MOLECULES AND USES THEREOF | WYETH LLC (US) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120014975-A1 | MODIFIED SINGLE DOMAIN ANTIGEN BINDING MOLECULES AND USES THEREOF | TNFSF11, CD40, CD2BP2 | KMT2A 3901/4885GAA 1004/4885ALDH1A1 3220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.