Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.53 |
| ▸ | PORCN | Q9H237 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17626299 | 0.87 | PORCN (0.59) | TRPA1PORCNCYP1A2L3MBTL1RAB9A | |
| SCHEMBL17626215 | 0.86 | L3MBTL1 (0.54) | TRPA1PORCNCYP1A2L3MBTL1KDM4E | |
| SCHEMBL17626216 | 0.84 | TSHR (0.53) | TRPA1PORCNCYP1A2L3MBTL1RAB9A | |
| SCHEMBL17626184 | 0.84 | RAB9A (0.61) | TRPA1PORCNCYP1A2L3MBTL1RAB9A | |
| SCHEMBL21935377 | 0.84 | TRPA1 (0.55) | TRPA1PORCNCYP1A2L3MBTL1RAB9A | |
| SCHEMBL17628656 | 0.83 | RAB9A (0.56) | TRPA1PORCNCYP1A2L3MBTL1RAB9A | |
| SCHEMBL21935664 | 0.83 | TRPA1 (0.52) | TRPA1PORCNCYP1A2L3MBTL1RAB9A | |
| SCHEMBL17626308 | 0.83 | MAPK1 (0.59) | TRPA1PORCNCYP1A2L3MBTL1RAB9A | |
| SCHEMBL17626187 | 0.83 | RAB9A (0.53) | TRPA1PORCNCYP1A2L3MBTL1RAB9A | |
| SCHEMBL21935372 | 0.83 | TRPA1 (0.52) | TRPA1PORCNCYP1A2L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999699-B1 | PURINE DIONES AS WNT PATHWAY MODULATORS | AGENCY SCIENCE TECH & RES (SG) | 2020-04-29 | — | — | EP | disclosed |