SCHEMBL21936668

SCHEMBL21936668

Nc1cccc2c1CCC21CCC1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD44 P16070 2/20 0.34
KDM1A O60341 2/20 0.34
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
PARP1 P09874 1/20 0.33
CYP3A4 P08684 2/20 0.30
TSHR P16473 2/20 0.30
TP53 P04637 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
DRD2 P14416 1/20 0.30
NFKB1 P19838 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24258225 0.92 KDM1A (0.35) CD44KDM1AALDH1A1HPGDKDM4E
SCHEMBL24258213 0.92 CD44 (0.36) CD44KDM1AALDH1A1HPGDKDM4E
SCHEMBL24258173 0.89 KDM1A (0.35) CD44KDM1AALDH1A1HPGDKDM4E
SCHEMBL23356013 0.74 CD44 (0.35) CD44KDM1AALDH1A1HPGDKDM4E
SCHEMBL9507986 0.74 ALDH1A1 (0.38) CD44KDM1AALDH1A1HPGDKDM4E
SCHEMBL30791259 0.74 CD44 (0.35) CD44KDM1AALDH1A1HPGDKDM4E
SCHEMBL15822259 0.72 KDM1A (0.41) CD44KDM1AALDH1A1HPGDKDM4E
SCHEMBL4814969 0.70 PARP1 (0.34) CD44KDM1AALDH1A1HPGDKDM4E
Hydrochloric Acid SCHEMBL15532871 0.70 KDM1A (0.40) CD44KDM1AALDH1A1HPGDKDM4E
SCHEMBL24258207 0.70 CES2 (0.38) CD44KDM1AALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020072835-A1 11,13-MODIFIED SAXITOXINS FOR THE TREATMENT OF PAIN SITEONE THERAPEUTICS, INC. (US) 2020-04-09 WO disclosed