Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.30 |
| ▸ | HTR5A | P47898 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27103162 | 0.85 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3HSD17B10HTR5A | |
| SCHEMBL29710439 | 0.75 | TRPA1 (0.38) | SLC6A2SLC6A4SLC6A3CYP2D6NOTUM | |
| SCHEMBL11441366 | 0.75 | TRPA1 (0.38) | SLC6A2SLC6A4SLC6A3CYP2D6NOTUM | |
| SCHEMBL28162719 | 0.69 | KDM4E (0.33) | — | |
| SCHEMBL255505 | 0.68 | HTR5A (0.37) | HTR5ANOTUM | |
| SCHEMBL8340988 | 0.68 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3CYP2D6HSD17B10 | |
| SCHEMBL30025550 | 0.65 | ADRA2A (0.34) | HTR5ANOTUM | |
| SCHEMBL7938077 | 0.65 | ADRA2A (0.34) | HTR5ANOTUM | |
| Hydrochloric Acid SCHEMBL11820690 | 0.64 | ADRA2A (0.33) | HTR5ANOTUM | |
| SCHEMBL2835665 | 0.63 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3633380-A1 | METHOD FOR PREDICTING THERAPEUTIC EFFECT OF LSD1 INHIBITOR BASED ON EXPRESSION OF INSM1 | Taiho Pharmaceutical Co., Ltd. (JP) | 2020-04-08 | — | — | EP | disclosed |