Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 14/20 | 0.40 |
| ▸ | SPR | P35270 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21858992 | 0.78 | CHRM1 (0.53) | CHRM1SPRSMN1; SMN2 | |
| SCHEMBL22322792 | 0.78 | CHRM1 (0.48) | CHRM1SPRTP53MAPT | |
| SCHEMBL25348205 | 0.72 | SPR (0.49) | SPRTP53MAPTSMN1; SMN2ADORA3 | |
| SCHEMBL21859079 | 0.72 | CHRM1 (0.64) | CHRM1SPR | |
| SCHEMBL21938332 | 0.71 | CHRM1 (0.61) | CHRM1SPR | |
| SCHEMBL25348758 | 0.69 | SPR (0.44) | SPRTP53MAPTSMN1; SMN2ADORA3 | |
| SCHEMBL30540553 | 0.67 | SPR (0.48) | SPRTP53MAPTSMN1; SMN2ADORA3 | |
| SCHEMBL24845746 | 0.67 | LPL (0.44) | — | |
| SCHEMBL1601462 | 0.66 | CYP2C19 (0.48) | TP53MAPTSMN1; SMN2 | |
| SCHEMBL24845743 | 0.66 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020079606-A9 | PYRROLO-PYRIDAZINE DERIVATIVES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LIMITED (IN) | 2020-08-13 | — | — | WO | disclosed |
| WO-2020079606-A1 | PYRROLO-PYRIDAZINE DERIVATIVES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LIMITED (IN) | 2020-04-23 | — | — | WO | disclosed |