Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15140161 | 0.81 | CA12 (0.44) | CA12CA1CA2CA9GAA | |
| SCHEMBL24119328 | 0.79 | CA12 (0.46) | CA12CA1CA2CA9 | |
| SCHEMBL2575973 | 0.76 | CA12 (0.42) | CA12CA1CA2CA9CA7 | |
| SCHEMBL4396144 | 0.74 | SLC7A5 (0.43) | — | |
| SCHEMBL1839770 | 0.72 | GAA (0.41) | NFKB1NFKB2RELAGAA | |
| SCHEMBL15148209 | 0.72 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL13498680 | 0.72 | ALDH1A1 (0.46) | CA12CA1CA9 | |
| SCHEMBL7990866 | 0.71 | CYP17A1 (0.38) | CA12CA1CA9NFKB1NFKB2 | |
| SCHEMBL20374749 | 0.71 | CA12 (0.47) | CA12CA1CA2CA9CA7 | |
| SCHEMBL13404895 | 0.70 | MGLL (0.37) | CA12CA1CA9SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020072784-A1 | IMAGING AGENTS AND METHODS OF USE | TEXAS HEART INSTITUTE (US) | 2020-04-09 | — | — | WO | disclosed |