Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.37 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13498680 | 0.84 | ALDH1A1 (0.46) | CYP17A1HPGDDRD2CA12CA1 | |
| SCHEMBL16318447 | 0.80 | KDM4E (0.52) | CYP17A1KCNQ4KCNQ5HPGDKDM4E | |
| SCHEMBL9890035 | 0.79 | RXFP1 (0.46) | HPGDKDM4EBRD9RXFP1 | |
| SCHEMBL22845018 | 0.78 | ALDH1A1 (0.40) | HPGDKDM4E | |
| SCHEMBL9494583 | 0.77 | SLC7A5 (0.44) | ALOX15SRD5A1CA12CA1CA9 | |
| SCHEMBL1839770 | 0.77 | GAA (0.41) | CYP17A1HPGDNFKB1NFKB2RELA | |
| SCHEMBL7910494 | 0.76 | ALOX15 (0.39) | ALOX15HPGDKDM4ESRD5A1CA12 | |
| SCHEMBL3256083 | 0.76 | NPC1 (0.54) | CYP17A1KCNQ4KCNQ5HPGDKDM4E | |
| SCHEMBL130859 | 0.76 | NAMPT (0.47) | CA1 | |
| SCHEMBL12995665 | 0.75 | PSMB8 (0.46) | CYP17A1DRD2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291198-B1 | REACTING 1,2-DICARBONYL DERIVATIVE WITH DIAMINE FOR IMMUNOLOGICAL DETERMINATION; MEASUREMENT OF ANTIGEN-ANTIBODY COMPLEX; DIABETES DIAGNOSIS | THE FUJIREBIO INC. (JP) | 2001-09-18 | — | — | US | disclosed |