Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 5/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.47 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 3/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3112717 | 0.93 | PTGES (0.59) | PTGESALOX5HDAC1HDAC6TAS2R14 | |
| Trifluoroacetic Acid SCHEMBL3128564 | 0.86 | PTGES (0.54) | PTGESALOX5HDAC1HDAC6OPRM1 | |
| SCHEMBL5722096 | 0.83 | OPRM1 (0.61) | HDAC1HDAC6RORCOPRM1OPRD1 | |
| Trifluoroacetic Acid SCHEMBL3127389 | 0.83 | CHRNB2 (0.49) | PTGESALOX5HDAC1HDAC6TAS2R14 | |
| SCHEMBL21940191 | 0.81 | SRD5A2 (0.61) | PTGESALOX5TAS2R14SRD5A2KMT2A | |
| SCHEMBL13658165 | 0.80 | HRH3 (0.53) | PTGESRORCOPRM1OPRD1OPRK1 | |
| Trifluoroacetic Acid SCHEMBL3126972 | 0.79 | PTGES (0.49) | PTGESALOX5TAS2R14RORCKMT2A | |
| Trifluoroacetic Acid SCHEMBL3113437 | 0.78 | OPRM1 (0.50) | PTGESALOX5OPRM1OPRD1OPRK1 | |
| SCHEMBL7721337 | 0.76 | OPRM1 (0.50) | HDAC1HDAC6RORCOPRM1OPRD1 | |
| SCHEMBL30093246 | 0.76 | OPRM1 (0.57) | HDAC1HDAC6RORCOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200131144-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | PHENEX-FXR GMBH (DE) | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131144-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | NR1H2, NR1H3, NR1H4 | PTGES 1053/4885ALOX5 1656/4885HDAC1 401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.