Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 6/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 4/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21940508 | 0.81 | GPR84 (0.41) | — | |
| SCHEMBL21940472 | 0.78 | SOS1 (0.41) | GRM5P2RX3P2RX2 | |
| SCHEMBL21940590 | 0.78 | IDH1 (0.37) | LOXL2 | |
| SCHEMBL21940466 | 0.75 | SYK (0.44) | GRM5LOXL2 | |
| SCHEMBL21940467 | 0.74 | IDH1 (0.36) | LOXL2SCN8A | |
| SCHEMBL20606969 | 0.73 | CA2 (0.39) | LOXL2 | |
| SCHEMBL20606883 | 0.72 | HSP90AA1 (0.42) | GRM5LOXL2 | |
| SCHEMBL24566255 | 0.70 | TLR7 (0.35) | TLR7 | |
| SCHEMBL30442165 | 0.70 | TLR7 (0.35) | TLR7 | |
| SCHEMBL5338216 | 0.69 | MCHR1 (0.63) | MCHR1XDHTLR7GRM5IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423445-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2020-04-01 | — | — | EP | disclosed |