Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 4/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 3/20 | 0.37 |
| ▸ | JAK1 | P23458 | 3/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23024480 | 1.00 | GPR119 (0.41) | GPR119TSHRALOX15NAMPTIDO1 | |
| SCHEMBL23024159 | 0.86 | ROCK2 (0.42) | GPR119TSHRALOX15NAMPTIDO1 | |
| SCHEMBL30568087 | 0.85 | GPR119 (0.39) | GPR119TSHRALOX15NAMPTJAK2 | |
| SCHEMBL23046133 | 0.82 | TSHR (0.44) | GPR119TSHRALOX15NAMPTIDO1 | |
| SCHEMBL29890956 | 0.82 | TSHR (0.44) | GPR119TSHRALOX15NAMPTIDO1 | |
| SCHEMBL21383837 | 0.82 | TSHR (0.44) | GPR119TSHRALOX15NAMPTIDO1 | |
| SCHEMBL23046137 | 0.77 | HDAC2 (0.41) | GPR119NAMPT | |
| SCHEMBL21383778 | 0.74 | USP30 (0.43) | GPR119NAMPTIDO1 | |
| SCHEMBL23046306 | 0.74 | HDAC2 (0.41) | GPR119NAMPT | |
| SCHEMBL30529609 | 0.74 | USP30 (0.43) | GPR119NAMPTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3768668-B1 | SHP2 PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS INC (US) | 2024-08-28 | — | — | EP | disclosed |