Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 18/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21940812 | 0.82 | FFAR2 (0.38) | ELOVL1FFAR2 | |
| SCHEMBL21940807 | 0.79 | LRRK2 (0.44) | — | |
| SCHEMBL21941078 | 0.79 | KDM4E (0.38) | ELOVL1FFAR2AR | |
| SCHEMBL21940286 | 0.71 | ALDH1A1 (0.42) | — | |
| SCHEMBL21941083 | 0.71 | PDE10A (0.36) | — | |
| SCHEMBL23327686 | 0.70 | AR (0.43) | ELOVL1FFAR2AR | |
| SCHEMBL30912115 | 0.70 | AR (0.43) | ELOVL1FFAR2AR | |
| SCHEMBL21940300 | 0.69 | PIM1 (0.31) | — | |
| SCHEMBL21940600 | 0.69 | LRRK2 (0.41) | FFAR2 | |
| SCHEMBL21941081 | 0.68 | AKT1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423445-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2020-04-01 | — | — | EP | disclosed |