Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MET | P08581 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21577670 | 0.82 | KMT2A (0.35) | KMT2AMAPK1MEN1L3MBTL1TDP1 | |
| SCHEMBL23874215 | 0.80 | KMT2A (0.37) | KMT2AMAPK1MEN1L3MBTL1TDP1 | |
| SCHEMBL21577671 | 0.74 | MAPT (0.36) | KMT2AMEN1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL19040901 | 0.74 | KMT2A (0.41) | KMT2AMAPK1MEN1L3MBTL1TDP1 | |
| SCHEMBL1104678 | 0.74 | KMT2A (0.46) | KMT2AMAPK1MEN1L3MBTL1TDP1 | |
| SCHEMBL22023973 | 0.72 | KMT2A (0.40) | KMT2AMAPK1MEN1L3MBTL1TDP1 | |
| SCHEMBL22332293 | 0.70 | KMT2A (0.42) | KMT2AMAPK1MEN1L3MBTL1TDP1 | |
| SCHEMBL6002955 | 0.68 | KMT2A (0.44) | KMT2AMAPK1MEN1L3MBTL1TDP1 | |
| SCHEMBL23597829 | 0.64 | ALDH1A1 (0.39) | KMT2AMAPK1MEN1L3MBTL1TDP1 | |
| SCHEMBL762080 | 0.64 | TP53 (0.47) | KMT2AMAPK1MEN1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200113913-A1 | METHODS FOR HAIR FOLLICLE STEM CELL PROLIFERATION | Frequency Therapeutics, Inc. | 2020-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200113913-A1 | METHODS FOR HAIR FOLLICLE STEM CELL PROLIFERATION | SHH, WNT3A, WNT1 | KMT2A 1917/4885MAPK1 1383/4885MEN1 4799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.