Acetic Acid

Acetic Acid

SCHEMBL2194348

C1=COc2ccccc2C1.CC(=O)O

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSD17B3 P37058 1/20 0.37
NOTUM Q6P988 5/20 0.36
KDM4E B2RXH2 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL11766149 0.98 GAA (0.38) GAASMN1; SMN2HSD17B3NOTUMKDM4E
Bicarbonate SCHEMBL2467504 0.93 MAOA (0.34) GAASMN1; SMN2HSD17B3NOTUMKDM4E
Bicarbonate SCHEMBL4853464 0.93 MAOA (0.34) GAASMN1; SMN2HSD17B3NOTUMKDM4E
Acetic Acid SCHEMBL10486833 0.92 GAA (0.34) GAASMN1; SMN2HSD17B3NOTUMKDM4E
Acetamide SCHEMBL7696552 0.91 SMN1; SMN2 (0.38) GAASMN1; SMN2HSD17B3NOTUMKDM4E
Pyridine SCHEMBL5593972 0.91 GAA (0.33) GAASMN1; SMN2HSD17B3NOTUMKDM4E
Hydrogen Peroxide SCHEMBL15163599 0.91 MAOA (0.38) GAASMN1; SMN2MAOAMAOBHTT
Acetic Acid SCHEMBL8700134 0.89 GAA (0.36) GAASMN1; SMN2HSD17B3NOTUM
Methyl Alcohol SCHEMBL7362934 0.89 MAOA (0.37) GAASMN1; SMN2HSD17B3MAOAMAOB
Propionic Acid SCHEMBL5157894 0.88 HTT (0.35) GAASMN1; SMN2HSD17B3NOTUMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7157072-B2 Cathode composition for lithium batteries and method of preparing the same ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2007-01-02 US claimed
US-20050069772-A1 Cathode composition for lithium batteries and method of preparing the same INTELLECTUAL DISCOVERY CO., LTD. (KR) 2005-03-31 US claimed
US-20040224853-A1 Drilling fluid additives JASINSKI RICARDO (AR) 2004-11-11 US claimed
US-4505825-A BORON-CHROME-LIGONOSULFONATE REED LIGNIN INC. (US) 1985-03-19 US claimed
US-11981864-B1 Temporary isolation system for reservoirs BAKER HUGHES OILFIELD OPERATIONS LLC (US) 2024-05-14 US disclosed
US-11834594-B2 Methods for drilling wellbores using thinner compositions CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2023-12-05 US disclosed
CN-114792770-A Display panel and display device 武汉天马微电子有限公司 2022-07-26 CN disclosed
EP-3953431-A1 METHODS FOR DRILLING WELLBORES USING THINNER COMPOSITIONS Chevron Phillips Chemical Company LP (US) 2022-02-16 EP disclosed
US-20210388253-A1 Methods for Drilling Wellbores Using Thinner Compositions CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2021-12-16 US disclosed
US-20200325380-A1 Methods for Drilling Wellbores Using Thinner Compositions CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2020-10-15 US disclosed
WO-2020210294-A1 METHODS FOR DRILLING WELLBORES USING THINNER COMPOSITIONS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2020-10-15 WO disclosed
US-10669387-B2 Thin film material for processing use TBM CO., LTD. (JP) 2020-06-02 US disclosed
EP-0106306-A2 Silver halide color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1984-04-25 EP disclosed
US-4421847-A ACTIVATION OF CARBOXYL GROUPS, PHOTOGRAPHIC FILMS AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1983-12-20 US disclosed
US-4308345-A CYANINE DYES FOR COLOR FUJI PHOTO FILM CO., LTD. (JP) 1981-12-29 US disclosed
US-4248963-A BY BACK COATING WITH AN AQUEOUS DISPERSION OF ANIONIC EMULSIFIER AND ACRYLIC-VINYL COPOLYMERS AGFA-GEVAERT, A.G. (DE) 1981-02-03 US disclosed
US-4216290-A Coating of viscous aqueous gelatin compositions on a continuous web support AGFA-GEVAERT N.V. (BE) 1980-08-05 US disclosed
US-4097284-A TRIMETHINECYANINE DYE AND A NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING A MERCAPTO FUJI PHOTO FILM CO., LTD. (JA) 1978-06-27 US disclosed
US-3984247-A Dye-containing silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-10-05 US disclosed
US-3966472-A SILVER HALIDE EMULSION FUJI PHOTO FILM CO., LTD. (JA) 1976-06-29 US disclosed