Acetamide

Acetamide

SCHEMBL7696552

C1=COc2ccccc2C1.CC(N)=O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.38
GAA P10253 1/20 0.38
HSD17B3 P37058 1/20 0.36
NOTUM Q6P988 4/20 0.35
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NISCH Q9Y2I1 1/20 0.33
ATM Q13315 1/20 0.33
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
PARP1 P09874 3/20 0.30
HTT P42858 1/20 0.30
NQO2 P16083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL2194348 0.91 GAA (0.39) SMN1; SMN2GAAHSD17B3NOTUMNPC1
Acetic Acid SCHEMBL11766149 0.90 GAA (0.38) SMN1; SMN2GAAHSD17B3NOTUMNPC1
Bicarbonate SCHEMBL2467504 0.87 MAOA (0.34) SMN1; SMN2GAAHSD17B3NOTUMKDM4E
Bicarbonate SCHEMBL4853464 0.87 MAOA (0.34) SMN1; SMN2GAAHSD17B3NOTUMKDM4E
Acetic Acid SCHEMBL10486833 0.87 GAA (0.34) SMN1; SMN2GAAHSD17B3NOTUMNPC1
Methyl Alcohol SCHEMBL7362934 0.87 MAOA (0.37) SMN1; SMN2GAAHSD17B3NISCHMAOA
Sulfuric Acid SCHEMBL4302708 0.87 LMNA (0.35) KDM4ENISCHATM
Hydrogen Peroxide SCHEMBL15163599 0.85 MAOA (0.38) SMN1; SMN2GAANISCHMAOAMAOB
SCHEMBL9209 0.85 MAOA (0.41) SMN1; SMN2GAAMAOAMAOBHTT
SCHEMBL29434883 0.85 MAOA (0.41) SMN1; SMN2GAAMAOAMAOBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002076938-A2 CARBOXYBENZOPYRAN DERIVATIVES AND COMPOSITIONS SONUS PHARMACEUTICALS, INC. (US) 2002-10-03 WO disclosed