Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TPH1 | P17752 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28362811 | 0.99 | GRIA2 (0.41) | GRIA2PPARGPPARASCN9ASLC7A5 | |
| Hydrochloric Acid SCHEMBL28362813 | 0.99 | GRIA2 (0.41) | GRIA2PPARGPPARASCN9ASLC7A5 | |
| SCHEMBL21946552 | 0.89 | SLC7A5 (0.44) | GRIA2PPARGPPARASLC7A5MAPT | |
| SCHEMBL21946649 | 0.89 | SLC7A5 (0.44) | GRIA2PPARGPPARASLC7A5MAPT | |
| SCHEMBL21946228 | 0.85 | GRIA2 (0.59) | GRIA2SLC7A5NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL21879189 | 0.84 | GRIA2 (0.58) | GRIA2SLC7A5NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL20502559 | 0.84 | GRIA2 (0.58) | GRIA2SLC7A5NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL21879188 | 0.84 | GRIA2 (0.58) | GRIA2SLC7A5NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL20502561 | 0.84 | GRIA2 (0.58) | GRIA2SLC7A5NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL30655647 | 0.84 | GRIA2 (0.58) | GRIA2SLC7A5NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11345669-B2 | Urea derivatives and methods of use thereof | NodThera Limited (GB) | 2022-05-31 | — | — | US | disclosed |
| US-20200131141-A1 | CHEMICAL COMPOUNDS | NodThera Limited (GB) | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131141-A1 | CHEMICAL COMPOUNDS | IL1B, CASP1, IL1A | GRIA2 3338/4885PPARG 867/4885PPARA 2135/4885 |
| US-11345669-B2 | Urea derivatives and methods of use thereof | IL1B, IL1A, NOD1 | GRIA2 4777/4885PPARG 2574/4885PPARA 3313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.