Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10021113 | 0.79 | METAP2 (0.47) | IDO1TDO2 | |
| SCHEMBL11631293 | 0.77 | IDO1 (0.45) | IDO1TDO2 | |
| SCHEMBL13232182 | 0.76 | EPHX1 (0.49) | IDO1TDO2 | |
| SCHEMBL20342450 | 0.73 | LMNA (0.47) | — | |
| SCHEMBL17664582 | 0.73 | CYP3A4 (0.40) | — | |
| SCHEMBL6075377 | 0.73 | TAAR1 (0.50) | — | |
| SCHEMBL12352043 | 0.73 | LMNA (0.47) | — | |
| SCHEMBL1495530 | 0.73 | CYP3A4 (0.40) | — | |
| SCHEMBL2272105 | 0.72 | KDM1A (0.43) | IDO1TDO2 | |
| SCHEMBL2272113 | 0.72 | KDM1A (0.43) | IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
| EP-2065369-A1 | UREA COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2009-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | FAAH, FAAH2, UTS2R | IDO1 516/4885TDO2 4083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.