Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GFER | P55789 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24176302 | 0.86 | ALDH1A1 (0.60) | ALDH1A1PKMPOLBKDM4EGAA | |
| SCHEMBL24176313 | 0.83 | HAGH (0.73) | ALDH1A1PKMPOLBKDM4EGAA | |
| SCHEMBL21951991 | 0.82 | ALDH1A1 (0.72) | ALDH1A1PKMKDM4EGAAKMT2A | |
| SCHEMBL8978522 | 0.81 | ALDH1A1 (0.73) | ALDH1A1PKMPOLBKDM4EGAA | |
| SCHEMBL21951961 | 0.80 | GLO1 (0.53) | ALDH1A1PKMPOLBKDM4EGAA | |
| SCHEMBL21951971 | 0.76 | KMT2A (0.55) | ALDH1A1KDM4EGAAKMT2AGFER | |
| SCHEMBL8978544 | 0.76 | ALDH1A1 (1.00) | ALDH1A1PKMPOLBKDM4EGAA | |
| SCHEMBL21952076 | 0.74 | TDP1 (0.72) | ALDH1A1PKMKDM4EGAAKMT2A | |
| SCHEMBL21952027 | 0.74 | ALDH1A1 (0.67) | ALDH1A1KDM4EGAAKMT2AHSD17B10 | |
| SCHEMBL21951965 | 0.72 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAAKMT2AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220000841-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES | UNIVERSITÉ DE MONTPELLIER (FR) | 2022-01-06 | — | — | US | claimed |
| EP-3653611-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-05-20 | — | — | EP | claimed |
| US-20220000841-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES | UNIVERSITÉ DE MONTPELLIER (FR) | 2022-01-06 | — | — | US | disclosed |
| US-20220000841-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES | UNIVERSITÉ DE MONTPELLIER (FR) | 2022-01-06 | — | — | US | disclosed |
| CN-113874357-A | Metallobeta-lactamase inhibitors | 国家科学研究中心 | 2021-12-31 | — | — | CN | disclosed |
| EP-3653611-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220000841-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES | MGAM, LCT, MGAM2 | ALDH1A1 547/4885PKM 2542/4885POLB 361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.