Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51601 | 0.91 | TDP1 (0.68) | TDP1SLC6A3KMT2ASLC6A2MAPK1 | |
| SCHEMBL28875175 | 0.91 | TDP1 (0.68) | TDP1SLC6A3KMT2ASLC6A2MAPK1 | |
| Propionic Acid SCHEMBL17135255 | 0.90 | LMNA (0.59) | TDP1SLC6A3KMT2ASLC6A2MAPK1 | |
| SCHEMBL14516200 | 0.90 | TDP1 (0.57) | TDP1SLC6A3KMT2ASLC6A2MAPK1 | |
| SCHEMBL17146850 | 0.89 | LMNA (0.58) | TDP1SLC6A3KMT2ASLC6A2MAPK1 | |
| SCHEMBL514789 | 0.88 | TDP1 (0.55) | TDP1SLC6A3KMT2ASLC6A2MAPK1 | |
| SCHEMBL14500880 | 0.88 | TDP1 (0.55) | TDP1SLC6A3KMT2ASLC6A2MAPK1 | |
| SCHEMBL14516201 | 0.88 | TDP1 (0.55) | TDP1SLC6A3KMT2ASLC6A2MAPK1 | |
| SCHEMBL20115287 | 0.88 | LMNA (0.61) | TDP1SLC6A3KMT2ASLC6A2MAPK1 | |
| SCHEMBL8661138 | 0.88 | TDP1 (0.66) | TDP1SLC6A3KMT2ASLC6A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150408-A2 | PURIFICATION OF BIS -QUATERNARY PYRIDINIUM OXIMES | SOUTHWEST RESEARCH INSTITUTE (US) | 2023-08-10 | — | — | WO | disclosed |
| US-20230242487-A1 | PURIFICATION OF BIS-QUATERNARY PYRIDINIUM OXIMES | DEFENSE THREAT REDUCTION AGENCY | 2023-08-03 | — | — | US | disclosed |
| US-20230242487-A1 | PURIFICATION OF BIS-QUATERNARY PYRIDINIUM OXIMES | DEFENSE THREAT REDUCTION AGENCY | 2023-08-03 | — | — | US | disclosed |
| EP-3891129-A1 | SYNTHESIS OF OXIME NERVE AGENT ANTIDOTES | SOUTHWEST RESEARCH INSTITUTE (US) | 2021-10-13 | — | — | EP | disclosed |
| WO-2020117525-A1 | SYNTHESIS OF OXIME NERVE AGENT ANTIDOTES | SOUTHWEST RESEARCH INSTITUTE (US) | 2020-06-11 | — | — | WO | disclosed |
| WO-2020117525-A1 | SYNTHESIS OF OXIME NERVE AGENT ANTIDOTES | SOUTHWEST RESEARCH INSTITUTE (US) | 2020-06-11 | — | — | WO | disclosed |
| US-10633340-B1 | Synthesis of oxime nerve agent antidotes | SOUTHWEST RESEARCH INSTITUTE (US) | 2020-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10633340-B1 | Synthesis of oxime nerve agent antidotes | ACHE, BCHE, PNPO | TDP1 296/4885SLC6A3 1875/4885KMT2A 1347/4885 |
| US-20230242487-A1 | PURIFICATION OF BIS-QUATERNARY PYRIDINIUM OXIMES | PNPO, BCHE, PLPBP | TDP1 191/4885SLC6A3 2360/4885KMT2A 2103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.