Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6322494 | 0.92 | KDM4E (0.42) | PPARAKDM4ECYP3A4CYP1A2NPC1 | |
| SCHEMBL6322485 | 0.92 | KDM4E (0.42) | PPARAKDM4ECYP3A4CYP1A2NPC1 | |
| SCHEMBL17440547 | 0.82 | KDM4E (0.45) | KDM4ECYP3A4CYP1A2NPC1CYP2D6 | |
| SCHEMBL16773339 | 0.82 | KDM4E (0.45) | KDM4ECYP3A4CYP1A2NPC1CYP2D6 | |
| SCHEMBL20640990 | 0.75 | NFE2L2 (0.38) | LMNATP53NQO2PTGS2NFE2L2 | |
| SCHEMBL15539518 | 0.75 | IDO1 (0.43) | PPARA | |
| SCHEMBL15539516 | 0.75 | IDO1 (0.43) | PPARA | |
| SCHEMBL3247170 | 0.74 | AHR (0.54) | LTB4RLTB4R2KDM4ECYP3A4CYP1A2 | |
| SCHEMBL3247166 | 0.74 | AHR (0.54) | LTB4RLTB4R2KDM4ECYP3A4CYP1A2 | |
| SCHEMBL3828085 | 0.74 | TDP1 (0.49) | ALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200123197-A1 | METHOD OF MAKING A CROSS METATHESIS PRODUCT | NATIONAL SCIENCE FOUNDATION | 2020-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200123197-A1 | METHOD OF MAKING A CROSS METATHESIS PRODUCT | DUOX2, DUOX1, RNF168 | PPARA 4522/4885LTB4R 667/4885LTB4R2 665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.