Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2199716 | 0.84 | AOC3 (0.41) | AOC3MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL2202724 | 0.81 | ALOX5 (0.43) | RIPK1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL4264543 | 0.80 | MEN1 (0.44) | AOC3MEN1KMT2AKDM4EHPGD | |
| SCHEMBL2197914 | 0.78 | MEN1 (0.41) | RIPK1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL2239284 | 0.75 | PPARA (0.41) | RIPK1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL2107176 | 0.75 | PPARA (0.41) | RIPK1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL2197629 | 0.74 | KDM4E (0.43) | AOC3RIPK1MEN1KMT2AKDM4E | |
| SCHEMBL2197829 | 0.74 | MTOR (0.31) | AOC3ALOX5 | |
| SCHEMBL2195384 | 0.74 | RIPK1 (0.37) | AOC3RIPK1MEN1KMT2AKDM4E | |
| SCHEMBL2196410 | 0.74 | RIPK1 (0.37) | AOC3RIPK1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977336-B2 | Aminopyrimidine derivatives as PLK1 inhibitors | BANYU PHARMACEUTICAL CO. LTD (JP) | 2011-07-12 | — | — | US | disclosed |