Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 6/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 6/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 6/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 5/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7235118 | 0.72 | GRIA1 (0.47) | MAPTLMNAKDM4EHTTNPSR1 | |
| SCHEMBL31714248 | 0.71 | GRIA1 (0.37) | MAPTLMNAKDM4EGRIA1GRIA2 | |
| SCHEMBL28237972 | 0.67 | MAPT (0.47) | MAPTLMNAKDM4EHTTNPSR1 | |
| SCHEMBL22748998 | 0.64 | GRIA1 (0.57) | MAPTLMNAKDM4EHTTGRIA1 | |
| SCHEMBL23211167 | 0.64 | GRIA1 (0.47) | MAPTLMNAKDM4EHTTNPSR1 | |
| SCHEMBL16174493 | 0.64 | GRIA1 (0.50) | MAPTLMNAKDM4EGRIA1GRIA2 | |
| SCHEMBL31710606 | 0.64 | — | — | |
| SCHEMBL14401140 | 0.62 | MAPT (0.46) | MAPTLMNAKDM4EHTTNPSR1 | |
| SCHEMBL7233498 | 0.62 | GRIA1 (0.58) | MAPTLMNAKDM4EGRIA1GRIA2 | |
| SCHEMBL11480035 | 0.61 | KDM4E (0.50) | MAPTLMNAKDM4EHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250333414-A1 | HETARYL SUBSTITUTED INDAZOLES AND BENZIMIDAZOLES AS STING ANTAGONISTS AND THE USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2025-10-30 | — | — | US | disclosed |
| EP-3478675-B1 | HETEROAROMATIC DERIVATIVES AS NIK INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250333414-A1 | HETARYL SUBSTITUTED INDAZOLES AND BENZIMIDAZOLES AS STING ANTAGONISTS AND THE USE THEREOF AS MEDICAMENT | STING1, MAVS, TBK1 | MAPT 4674/4885LMNA 1755/4885KDM4E 2677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.