Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 6/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | HMGCR | P04035 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20927213 | 0.84 | ALDH1A1 (0.50) | SLC13A5ADRA1AKEAP1MEN1KMT2A | |
| SCHEMBL7450180 | 0.83 | SLC13A5 (0.50) | SLC13A5ADRA1ACYP2C19HIF1AKEAP1 | |
| SCHEMBL24137647 | 0.83 | CA12 (0.46) | SLC13A5POLBKDM4ELMNAHDAC3 | |
| SCHEMBL24137653 | 0.83 | CA12 (0.46) | SLC13A5POLBKDM4ELMNAHDAC3 | |
| SCHEMBL27820002 | 0.82 | SLC13A5 (0.56) | SLC13A5ADRA1AHMGCRCHRM1TBXA2R | |
| SCHEMBL23080147 | 0.80 | LMNA (0.50) | CYP2C19MEN1KMT2ALMNAALDH1A1 | |
| Acetic Acid SCHEMBL15914114 | 0.80 | ALDH1A1 (0.48) | SLC13A5ADRA1AKEAP1POLBMEN1 | |
| SCHEMBL9419036 | 0.79 | SLC13A5 (0.46) | SLC13A5ADRA1ACYP2C19HIF1AKEAP1 | |
| SCHEMBL6632235 | 0.79 | ALDH1A1 (0.50) | SLC13A5ADRA1AHIF1AKEAP1POLB | |
| SCHEMBL5475208 | 0.79 | ALDH1A1 (0.50) | SLC13A5ADRA1AHIF1AKEAP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210403445-A1 | SYSTEMS AND METHODS FOR REGIOSELECTIVE CARBONYLATION OF 2,2-DISUBSTITUTED EPOXIDES | CORNELL UNIVERSITY | 2021-12-30 | — | — | US | disclosed |
| WO-2020102816-A1 | SYSTEMS AND METHODS FOR REGIOSELECTIVE CARBONYLATION OF 2,2-DISUBSTITUTED EPOXIDES | CORNELL UNIVERSITY (US) | 2020-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210403445-A1 | SYSTEMS AND METHODS FOR REGIOSELECTIVE CARBONYLATION OF 2,2-DISUBSTITUTED EPOXIDES | LTC4S, LSS, CYCS | SLC13A5 3820/4885ADRA1A 2577/4885HMGCR 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.