Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2194586 | 0.80 | FAAH (0.48) | GPR119ALDH1A1 | |
| SCHEMBL31752479 | 0.80 | CHEK2 (0.56) | GPR119CHEK2 | |
| SCHEMBL13806526 | 0.79 | FAAH (0.49) | HRH3 | |
| SCHEMBL12420619 | 0.78 | HRH3 (0.55) | HRH3 | |
| SCHEMBL20160543 | 0.78 | TP53 (0.48) | GPR119ALDH1A1 | |
| SCHEMBL25396199 | 0.77 | GPR119 (0.58) | GPR119CHEK2 | |
| Hydrochloric Acid SCHEMBL2195589 | 0.77 | HRH3 (0.54) | HRH3 | |
| SCHEMBL20788464 | 0.77 | VEGFA (0.53) | GPR119ALDH1A1 | |
| SCHEMBL12367628 | 0.77 | KDM4E (0.45) | GPR119HRH3ALDH1A1 | |
| SCHEMBL31752455 | 0.76 | GPR119 (0.56) | GPR119CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
| EP-2065369-A1 | UREA COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2009-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | FAAH, FAAH2, UTS2R | GPR119 741/4885HRH3 94/4885CHEK2 4539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.