Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.60 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.59 |
| ▸ | CDK2 | P24941 | 1/20 | 0.59 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.59 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.56 |
| ▸ | ACP1 | P24666 | 1/20 | 0.56 |
| ▸ | SCD | O00767 | 1/20 | 0.55 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2896337 | 0.81 | NR3C1 (0.62) | KDRCCNE1CDK2CDK5GSTO1 | |
| SCHEMBL5840422 | 0.79 | KDR (0.72) | KDRCCNE1CDK2CDK5GSTO1 | |
| SCHEMBL5835618 | 0.78 | CCNE1 (0.69) | KDRCCNE1CDK2CDK5GSTO1 | |
| SCHEMBL28014843 | 0.77 | KDR (0.62) | KDRCCNE1CDK2CDK5GSTO1 | |
| SCHEMBL10079021 | 0.76 | KDR (0.53) | KDRCCNE1CDK2CDK5GSTO1 | |
| SCHEMBL69753 | 0.76 | CCNE1 (0.74) | KDRCCNE1CDK2CDK5GSTO1 | |
| SCHEMBL17014785 | 0.76 | KDR (0.68) | KDRCCNE1CDK2CDK5GSTO1 | |
| SCHEMBL10252594 | 0.76 | KDR (1.00) | KDRCCNE1CDK2CDK5GSTO1 | |
| SCHEMBL2256136 | 0.76 | KDR (0.72) | KDRCCNE1CDK2CDK5GSTO1 | |
| SCHEMBL70693 | 0.74 | CCNE1 (0.63) | KDRCCNE1CDK2CDK5GSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102472-A1 | METHODS AND COMPOSITIONS RELATED TO TARGETING FFAR2 AND ILC3 POPULATIONS FOR THE TREATMENT OF A GASTROINTESTINAL DISEASE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-05-22 | — | — | WO | claimed |