SCHEMBL21963548

SCHEMBL21963548

Cc1ccc(S(=O)(=O)n2cc(B3OC(C)(C)C(C)(C)O3)c3cccc(N)c32)cc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.39
▸ UBE2N P61088 1/20 0.39
▸ HTR6 P50406 6/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ CYP19A1 P11511 1/20 0.37
▸ PKM P14618 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ ELANE P08246 1/20 0.34
▸ PRTN3 P24158 1/20 0.34
▸ RAPGEF4 Q8WZA2 1/20 0.34
▸ ALOX5 P09917 3/20 0.34
▸ PTGS2 P35354 1/20 0.34
▸ CA1 P00915 1/20 0.34
▸ CA2 P00918 1/20 0.34
▸ JAK2 O60674 1/20 0.34
▸ BTK Q06187 1/20 0.34
▸ ALK Q9UM73 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21068128 0.88 JAK2 (0.46) KDM4EUBE2NHTR6L3MBTL1CYP19A1
SCHEMBL21058468 0.87 HTR6 (0.39) KDM4EUBE2NHTR6L3MBTL1CYP19A1
SCHEMBL12011379 0.86 HTR6 (0.45) KDM4EUBE2NHTR6L3MBTL1PKM
SCHEMBL16968327 0.85 KDM4E (0.37) KDM4EUBE2NHTR6L3MBTL1CYP19A1
SCHEMBL18662607 0.85 HTR6 (0.39) KDM4EUBE2NHTR6L3MBTL1PKM
SCHEMBL28604693 0.84 RAPGEF4 (0.35) HTR6RAPGEF4JAK2BTK
SCHEMBL10182014 0.82 KDM4E (0.56) KDM4EUBE2NHTR6L3MBTL1CYP19A1
SCHEMBL29414046 0.82 KDM4E (0.56) KDM4EUBE2NHTR6L3MBTL1CYP19A1
SCHEMBL31395395 0.80 BRD4 (0.41) KDM4EUBE2NHTR6L3MBTL1PKM
SCHEMBL21870788 0.79 L3MBTL1 (0.35) KDM4EUBE2NL3MBTL1CYP19A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3880671-B1 NOVEL COMPOUND AS PROTEIN KINASE INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THEREOF HK INNO N CORP (KR) 2025-03-12 — — EP disclosed
US-12180185-B2 Compound as protein kinase inhibitor, and pharmaceutical composition comprising thereof HK INNO.N CORPORATION (KR) 2024-12-31 — — US disclosed
US-20220009902-A1 NOVEL COMPOUND AS PROTEIN KINASE INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THEREOF HK INNO.N CORPORATION (KR) 2022-01-13 — — US disclosed
EP-3880671-A1 NOVEL COMPOUND AS PROTEIN KINASE INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THEREOF HK inno.N Corporation (KR) 2021-09-22 — — EP disclosed
WO-2020101382-A1 NOVEL COMPOUND AS PROTEIN KINASE INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THEREOF HK INNO.N CORPORATION (KR) 2020-05-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12180185-B2 Compound as protein kinase inhibitor, and pharmaceutical composition comprising thereof MAP3K20, MAP3K1, MAP3K15 KDM4E 1696/4885UBE2N 3030/4885HTR6 4253/4885
US-20220009902-A1 NOVEL COMPOUND AS PROTEIN KINASE INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THEREOF MAP3K20, MAP3K1, MAP3K15 KDM4E 1970/4885UBE2N 2901/4885HTR6 4291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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